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Our Science – Casellas Website

Rafael Casellas, Ph.D.

Selected Publications

1)  Kieffer Kwon K, Tang Z, Mathe E, Qian J, Sung M, Li G, Resch W, Baek S, Pruett N, GrØntved L, Vian L, Nelson S, Hakim O, Reyon D, Yamane A, Nakahashi H, Kovalchuk A, Zou J, Joung JK, Sartorelli V, Wei C, Ruan X, Hager GL, Ruan Y, Casellas R.
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.
Cell. 2013.
In Press. [Journal]
2)  Kouzine F, Wojtowicz D, Yamane A, Resch W, Kieffer-Kwon KR, Bandle R, Nelson S, Nakahashi H, Awasthi P, Feigenbaum L, Menoni H, Hoeijmakers J, Vermeulen W, Ge H, Przytycka TM, Levens D, Casellas R.
Global regulation of promoter melting in naive lymphocytes.
Cell. 153: 988-99, 2013.
3)  Jankovic M, Feldhahn N, Oliveira TY, Silva IT, Kieffer-Kwon K, Yamane A, Resch W, Klein I, Robbiani DF, Casellas R, Nussenzweig MC.
53BP1 Alters the Landscape of DNA Rearrangements and Suppresses AID-Induced B Cell Lymphoma.
Mol. Cell. 49: 623-31, 2013.
4)  Yamane A, Robbiani DF, Resch W, Bothmer A, Nakahashi H, Oliveira T, Rommel PC, Brown EJ, Nussenzweig A, Nussenzweig MC, Casellas R.
RPA Accumulation during Class Switch Recombination Represents 5"-3" DNA-End Resection during the S-G2/M Phase of the Cell Cycle.
Cell Rep. 3: 138-47, 2013.
5)  Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W, Wang R, Green DR, Tessarollo L, Casellas R, Zhao K, Levens D.
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells.
Cell. 151: 68-79, 2012.
6)  Barlow JH, Faryabi RB, Callén E, Wong N, Malhowski A, Chen HT, Gutierrez-Cruz G, Sun HW, McKinnon P, Wright G, Casellas R, Robbiani DF, Staudt L, Fernandez-Capetillo O, Nussenzweig A.
Identification of Early Replicating Fragile Sites that Contribute to Genome Instability.
Cell. 152: 620-32, 2013.
7)  Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R.
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Nature. 484: 69-74, 2012.
8)  Di Virgilio M, Callen E, Yamane A, Zhang W, Jankovic M, Gitlin AD, Feldhahn N, Resch W, Oliveira TY, Chait BT, Nussenzweig A, Casellas R, Robbiani DF, Nussenzweig MC.
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Science. 339: 711-5, 2013.
9)  Yamane A, Resch W, Kuo N, Kuchen S, Li Z, Sun HW, Robbiani DF, McBride K, Nussenzweig MC, Casellas R.
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes.
Nat. Immunol. 12: 62-9, 2011.
10)  Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC.
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Cell. 147: 95-106, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 11/26/2013.