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Our Science – Mock Website

Beverly Mock, Ph.D.

Selected Publications

1)  Simmons JK, Patel J, Michalowski A, Zhang S, Wei BR, Sullivan P, Gamache B, Felsenstein K, Kuehl WM, Simpson RM, Zingone A, Landgren O, Mock BA.
TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms.
Mol Oncol. 8: 261-72, 2014.
[Journal]
2)  Zhang S, Pruitt M, Tran D, Du Bois W, Zhang K, Patel R, Hoover S, Simpson RM, Simmons J, Gary J, Snapper CM, Casellas R, Mock BA.
B Cell-Specific Deficiencies in mTOR Limit Humoral Immune Responses.
J. Immunol. 191: 1692-703, 2013.
[Journal]
3)  Zhang S, Readinger JA, DuBois W, Janka-Junttila M, Robinson R, Pruitt M, Bliskovsky V, Wu JZ, Sakakibara K, Patel J, Parent CA, Tessarollo L, Schwartzberg PL, Mock BA.
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.
Blood. 117: 1228-38, 2011.
[Journal]
4)  Wu JJ, Liu J, Chen EB, Wang JJ, Cao L, Narayan N, Fergusson MM, Rovira II, Allen M, Springer DA, Lago CU, Zhang S, Dubois W, Ward T, Decabo R, Gavrilova O, Mock B, Finkel T.
Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression.
Cell Rep. 4: 913-20, 2013.
[Journal]
5)  Zhang K, Kagan D, Dubois W, Robinson R, Bliskovsky V, Vass WC, Zhang S, Mock BA.
Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth and may modify plasmacytoma susceptibility.
Blood. 114: 2952-60, 2009.
[Journal]
6)  Smrž D, Bandara G, Zhang S, Mock BA, Beaven MA, Metcalfe DD, Gilfillan AM.
A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses.
J. Immunol. Methods. 390: 52-62, 2013.
[Journal]
7)  Simmons JK, Amlin-Van Schaick JC, Geiger TR, Reilly K, Hunter K, Mock BA.
Mouse genetics 2011: meeting report.
Mamm. Genome. 23: 225-31, 2012.
[Journal]
8)  Liu Z, Yang X, Li Z, McMahon C, Sizer C, Barenboim-Stapleton L, Bliskovsky V, Mock B, Ried T, London WB, Maris J, Khan J, Thiele CJ.
CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression.
Cell Death Differ. 18: 1174-83, 2011.
[Journal]
9)  Smrz D, Kim MS, Zhang S, Mock BA, Smrzová S, DuBois W, Simakova O, Maric I, Wilson TM, Metcalfe DD, Gilfillan AM.
mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.
Blood. 118: 6803-13, 2011.
[Journal]
10)  Mock BA, Zhang S, Ramsay ES, Bliskovsky V, Zhang K, Shi W, DuBois W.
Strategies for dissecting complex traits associated with cancer: lessons from plasma cell tumors. In: AACR Education Book 2005.
Philadelphia: AACR; 2005. p. 273-276 [Book Chapter]
11)  Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium .
The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Nat Genet. 36: 1133-7, 2004.
[Journal]
12)  Bliskovsky V, Ramsay ES, Scott J, DuBois W, Shi W, Zhang S, Qian X, Lowy DR, Mock BA.
Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Proc Natl Acad Sci U S A. 100: 14982-7, 2003.
[Journal]
13)  Zhang S, Qian X, Redman C, Bliskovski V, Ramsay ES, Lowy DR, Mock BA.
p16(INK4a) gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.
Oncogene. 22: 2285-95, 2003.
[Journal]
14)  Zhang SL, DuBois W, Ramsay ES, Bliskovski V, Morse HC, Taddesse-Heath L, Vass WC, DePinho RA, Mock BA.
Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility.
Mol Cell Biol. 21: 310-8, 2001.
[Journal]
15)  Masat L, Liddell RA, Mock BA, Kuo WL, Jessberger R, Wabl M, Morse HC.
Mapping of the SWAP70 gene to mouse chromosome 7 and human chromosome 11p15.
Immunogenetics. 51: 16-9, 2000.
[Journal]
16)  Bliskovski V, Liddell R, Ramsay ES, Miller MJ, Mock BA.
Structure and localization of mouse Pmscl1 and Pmscl2 genes.
Genomics. 64: 106-10, 2000.
[Journal]
17)  Liddell RA, Hirano MC, Mock BA.
Mouse chromosome 4.
Mamm Genome. 10: 943, 1999.
[Journal]
18)  Zhang S, Ramsay ES, Mock BA.
Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.
Proc Natl Acad Sci U S A. 95: 2429-34, 1998.
[Journal]
19)  Mock BA, Lowry DT, Rehman I, Padlan C, Yuspa SH, Hennings H.
Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.
Carcinogenesis. 19: 1109-15, 1998.
[Journal]
20)  Mock BA, Hartley J, Le Tissier P, Wax JS, Potter M.
The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4.
Blood. 90: 4092-8, 1997.
[Journal]
21)  Mock BA, Krall MM, Dosik JK.
Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis.
Proc Natl Acad Sci U S A. 90: 9499-503, 1993.
[Journal]
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This page was last updated on 5/8/2014.