Our Science – Kedei Website
Noemi Kedei, M.D.
Selected Publications |
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| 1)
Pu Y, Garfield SH, Kedei N, Blumberg PM. Characterization of the differential roles of the twin C1a and C1b domains of protein kinase C-delta. J. Biol. Chem. 284: 1302-12, 2009. [Journal] |
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| 2)
Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. J. Med. Chem. 52: 3274-83, 2009. [Journal] |
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| 3)
Keck GE, Poudel YB, Welch DS, Kraft MB, Truong AP, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters. Org. Lett. 11: 593-6, 2009. [Journal] |
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| 4)
Keck GE, Li W, Kraft MB, Kedei N, Lewin NE, Blumberg PM. The bryostatin 1 A-ring acetate is not the critical determinant for antagonism of phorbol ester-induced biological responses. Org. Lett. 11: 2277-80, 2009. [Journal] |
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| 5)
Choi SH, Czifra G, Kedei N, Lewin NE, Lazar J, Pu Y, Marquez VE, Blumberg PM. Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta. J. Biol. Chem. 283: 10543-9, 2008. [Journal] |
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| 6)
Duan D, Sigano DM, Kelley JA, Lai CC, Lewin NE, Kedei N, Peach ML, Lee J, Abeyweera TP, Rotenberg SA, Kim H, Kim YH, El Kazzouli S, Chung JU, Young HA, Young MR, Baker A, Colburn NH, Haimovitz-Friedman A, Truman JP, Parrish DA, Deschamps JR, Perry NA, Surawski RJ, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities. J. Med. Chem. 51: 5198-220, 2008. [Journal] |
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| 7)
Keck GE, Kraft MB, Truong AP, Li W, Sanchez CC, Kedei N, Lewin NE, Blumberg PM. Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-Alikes That Mimic Phorbol Ester Function. J. Am. Chem. Soc. 2008. [Journal] |
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| 8)
Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the ACS journal of surfaces and colloids. 24: 11043-52, 2008. [Journal] |
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| 9)
Blumberg PM, Kedei N, Lewin NE, Yang D, Czifra G, Pu Y, Peach ML, Marquez VE. Wealth of opportunity - the C1 domain as a target for drug development. Current drug targets. 9: 641-52, 2008. [Journal] |
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| 10)
Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups. J. Med. Chem. 50: 962-78, 2007. [Journal] |
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This page was last updated on 9/24/2009.
