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Our Science – Yuspa Website

Stuart H. Yuspa, M.D.

Selected Publications

1)  Mascia F, Lam G, Keith C, Garber C, Steinberg SM, Kohn E, Yuspa SH.
Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy.
Sci Transl Med. 5: 199ra110, 2013.
2)  Shukla A, Edwards R, Yang Y, Hahn A, Folkers K, Ding J, Padmakumar VC, Cataisson C, Suh KS, Yuspa SH.
CLIC4 regulates TGF-beta-dependent myofibroblast differentiation to produce a cancer stroma.
Oncogene. 33:: 842-50, 2014.
3)  Cataisson C, Salcedo R, Hakim S, Moffitt BA, Wright L, Yi M, Stephens R, Dai RM, Lyakh L, Schenten D, Yuspa HS, Trinchieri G.
IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis.
J. Exp. Med. 209: 1689-702, 2012.
4)  Suh KS, Malik M, Shukla A, Ryscavage A, Wright L, Jividen K, Crutchley JM, Dumont RA, Fernandez-Salas E, Webster JD, Simpson RM, Yuspa SH.
CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.
Carcinogenesis. 33: 986-95, 2012.
5)  Malik M, Jividen K, Padmakumar VC, Cataisson C, Li L, Lee J, Howard OM, Yuspa SH.
Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation.
Proc. Natl. Acad. Sci. U.S.A. 109: 6130-5, 2012.
6)  Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR.
Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
Circulation. 129: 1770-80, 2014.
7)  Padmakumar VC, Masiuk KE, Luger D, Lee C, Coppola V, Tessarollo L, Hoover SB, Karavanova I, Buonanno A, Simpson RM, Yuspa SH.
Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line.
BMC Dev. Biol. 14: 24, 2014.
8)  Salcedo R, Cataisson C, Hasan U, Yuspa SH, Trinchieri G.
MyD88 and its divergent toll in carcinogenesis.
Trends Immunol. 34: 379-89, 2013.
9)  Hattinger E, Zwicker S, Ruzicka T, Yuspa SH, Wolf R.
Opposing functions of psoriasin (S100A7) and koebnerisin (S100A15) in epithelial carcinogenesis.
Curr Opin Pharmacol. 13: 588-94, 2013.
10)  Ansbro MR, Shukla S, Ambudkar SV, Yuspa SH, Li L.
Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference.
PLoS ONE. 8: e60334, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 6/4/2014.