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Our Science – Flanders Website

Kathleen C. Flanders, Ph.D.

Selected Publications

1)  Latella G, Vetuschi A, Sferra R, Zanninelli G, D'Angelo A, Catitti V, Caprilli R, Flanders KC, Gaudio E.
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis.
Eur. J. Clin. Invest. 39: 145-56, 2009.
2)  Latella G, Vetuschi A, Sferra R, Catitti V, D'Angelo A, Zanninelli G, Flanders KC, Gaudio E.
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice.
Liver Int. 2009.
3)  Flanders KC, Wakefield LM.
Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.
Journal of mammary gland biology and neoplasia. 14: 131-44, 2009.
4)  Flanders KC, Ho BM, Arany PR, Stuelten C, Mamura M, Paterniti MO, Sowers A, Mitchell JB, Roberts AB.
Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.
Am. J. Pathol. 173: 68-76, 2008.
5)  Saika S, Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Sumioka T, Shirai K, Kitano A, Miyazaki K, Tanaka S, Ikeda K.
Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis.
Endocrine, metabolic & immune disorders drug targets. 8: 69-76, 2008.
6)  Arany PR, Flanders KC, Degraff W, Cook J, Mitchell JB, Roberts AB.
Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts.
J Dermatol Sci. 2007.
7)  Saika S, Yamanaka O, Okada Y, Miyamoto T, Kitano A, Flanders KC, Ohnishi Y, Nakajima Y, Kao WW, Ikeda K.
Effect of overexpression of ppar{gamma} on the healing process of corneal alkali burn in mice.
Am. J. Physiol., Cell Physiol. 293: C75-86, 2007.
8)  Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K.
Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model.
Arch. Ophthalmol. 125: 647-54, 2007.
9)  Saika S, Shirai K, Yamanaka O, Miyazaki K, Okada Y, Kitano A, Flanders KC, Kon S, Uede T, Kao WW, Rittling SR, Denhardt DT, Ohnishi Y.
Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium.
Lab. Invest. 87: 130-8, 2007.
10)  Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW.
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.
Mol. Cancer Ther. 6: 154-62, 2007.
Click Here to View Expanded Bibliography.

This page was last updated on 6/11/2009.