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Our Science – Tang Website

Binwu Tang, Ph.D.

Selected Publications

1)  Kohn EA, Du Z, Sato M, Van Schyndle CM, Welsh MA, Yang YA, Stuelten CH, Tang B, Ju W, Bottinger EP, Wakefield LM.
A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFß signaling in the mammary gland.
Breast Cancer Res. 12: R83, 2010.
[Journal]
2)  Kim RJ, Kim SR, Roh KJ, Park SB, Park JR, Kang KS, Kong G, Tang B, Yang YA, Kohn EA, Wakefield LM, Nam JS.
Ras activation contributes to the maintenance and expansion of Sca-1pos cells in a mouse model of breast cancer.
Cancer Lett. 287: 172-81, 2010.
[Journal]
3)  Stuelten CH, Busch JI, Tang B, Flanders KC, Oshima A, Sutton E, Karpova TS, Roberts AB, Wakefield LM, Niederhuber JE.
Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer.
PLoS ONE. 5: e9832, 2010.
[Journal]
4)  Nam JS, Terabe M, Mamura M, Kang MJ, Chae H, Stuelten C, Kohn E, Tang B, Sabzevari H, Anver MR, Lawrence S, Danielpour D, Lonning S, Berzofsky JA, Wakefield LM.
An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.
Cancer Res. 68: 3835-43, 2008.
[Journal]
5)  Tang B, Yoo N, Vu M, Mamura M, Nam JS, Ooshima A, Du Z, Desprez PY, Anver MR, Michalowska AM, Shih J, Parks WT, Wakefield LM.
Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.
Cancer Res. 67: 8643-52, 2007.
[Journal]
6)  Tang B, Vu M, Booker T, Santner SJ, Miller FR, Anver MR, Wakefield LM.
TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.
J. Clin. Invest. 112: 1116-24, 2003.
[Journal]
7)  Tang B, de Castro K, Barnes HE, Parks WT, Stewart L, Böttinger EP, Danielpour D, Wakefield LM.
Loss of responsiveness to transforming growth factor beta induces malignant transformation of nontumorigenic rat prostate epithelial cells.
Cancer Res. 59: 4834-42, 1999.
[Journal]
8)  Tang B, Böttinger EP, Jakowlew SB, Bagnall KM, Mariano J, Anver MR, Letterio JJ, Wakefield LM.
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.
Nat. Med. 4: 802-7, 1998.
[Journal]
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This page was last updated on 4/15/2014.