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Our Science – Amarnath Website

Shoba M. Amarnath, Ph.D.

Selected Publications

1)  Amarnath S.
c-Rel in GVHD biology: A missing link.
Eur.J.Immunol. 43(9): 2255-2258, 2013.
[Journal]
2)  Felizardo TC, Foley J, Steed K, Dropulic B, Amarnath S, Medin JA, Fowler DH.
Harnessing autophagy for cell fate control gene therapy.
Autophagy. 9, 2013.
[Journal]
3)  Amarnath S, Barrett AJ.
Mesenchymal stromal cells: heroes or non-combatants?.
Cytotherapy. 15: 253-4, 2013.
[Journal]
4)  Mangus CW, Massey PR, Fowler DH, Amarnath S.
Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity.
PLoS ONE. 8: e72305, 2013.
[Journal]
5)  Klionsky et al DJ.
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy. 8: 445-544, 2012.
[Journal]
6)  Vázquez N, Rekka S, Gliozzi M, Feng CG, Amarnath S, Orenstein JM, Wahl SM.
Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17.
J. Infect. Dis. 206: 1206-17, 2012.
[Journal]
7)  *Laurence A, *Amarnath S, Mariotti J, Kim YC, Foley J, Eckhaus M, O'Shea JJ, Fowler DH.
STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease. (*equally contributing authors).
Immunity. 37: 209-22, 2012.
[Journal]
8)  Amarnath S, Fowler DH.
Harnessing autophagy for adoptive T-cell therapy.
Immunotherapy. 4: 1-4, 2012.
[Journal]
9)  Miller TW, Wang EA, Gould S, Stein EV, Kaur S, Lim L, Amarnath S, Fowler DH, Roberts DD.
Hydrogen sulfide is an endogenous potentiator of T cell activation.
The Journal of biological chemistry. 2011.
[Journal]
10)  Amarnath S, *Mangus CW, *Wang JC, Wei F, He A, Kapoor V, Foley JE, Massey PR, Felizardo TC, Riley JL, Levine BL, June CH, Medin JA, Fowler DH.
The PDL1-PD1 Axis Converts Human Th1 Cells into Regulatory T Cells. (*equally contributing authors).
Sci Transl Med. 3: 111ra120, 2011.
[Journal]
11)  *Amarnath S, *Chen H, Foley JE, Costanzo CM, Sennesh JD, Solomon MA, Fowler DH.
Host-based th2 cell therapy for prolongation of cardiac allograft viability (*equally contributing authors).
PLoS ONE. 6: e18885, 2011.
[Journal]
12)  *Mariotti J, *Taylor J, Massey PR, Ryan K, Foley J, Buxhoeveden N, Felizardo TC, Amarnath S, Mossoba ME, Fowler DH.
The pentostatin plus cyclophosphamide nonmyeloablative regimen induces durable host T cell functional deficits and prevents murine marrow allograft rejection. (* equally contributing authors).
Biol. Blood Marrow Transplant. 17: 620-31, 2011.
[Journal]
13)  Amarnath S, Flomerfelt FA, Costanzo CM, Foley JE, Mariotti J, Konecki DM, Gangopadhyay A, Eckhaus M, Wong S, Levine BL, June CH, Fowler DH.
Rapamycin generates anti-apoptotic human Th1/Tc1 cells via autophagy for induction of xenogeneic GVHD.
Autophagy. 6, 2010.
[Journal]
14)  Amarnath S, Costanzo CM, Mariotti J, Ullman JL, Telford WG, Kapoor V, Riley JL, Levine BL, June CH, Fong T, Warner NL, Fowler DH.
Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.
PLoS Biol. 8: e1000302, 2010.
[Journal]
15)  Mariotti J, Foley J, Ryan K, Buxhoeveden N, Kapoor V, Amarnath S, Fowler DH.
Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway.
Blood. 112: 4765-75, 2008.
[Journal]
16)  Alhamarneh O, Amarnath SM, Stafford ND, Greenman J.
Regulatory T cells: what role do they play in antitumor immunity in patients with head and neck cancer?.
Head Neck. 30: 251-61, 2008.
[Journal]
17)  Amarnath S, Dong L, Li J, Wu Y, Chen W.
Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells.
Retrovirology. 4: 57, 2007.
[Journal]
18)  Nandula SR, Amarnath S, Molinolo A, Bandyopadhyay BC, Hall B, Goldsmith CM, Zheng C, Larsson J, Sreenath T, Chen W, Ambudkar IS, Karlsson S, Baum BJ, Kulkarni AB.
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.
Arthritis Rheum. 56: 1798-805, 2007.
[Journal]
19)  Liu Y, Amarnath S, Chen W.
Requirement of CD28 signaling in homeostasis/survival of TGF-beta converted CD4+CD25+ Tregs from thymic CD4+CD25- single positive T cells.
Transplantation. 82: 953-64, 2006.
[Journal]
20)  Amarnath SM, Dyer CE, Ramesh A, Iwuagwu O, Drew PJ, Greenman J.
In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer.
Int. J. Oncol. 25: 211-7, 2004.
[Journal]
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This page was last updated on 9/9/2013.