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Our Science – Klinman Website

Dennis M. Klinman, M.D., Ph.D.

Selected Publications

1)  Shi G, Vistica BP, Nugent LF, Tan C, Wawrousek EF, Klinman DM, Gery I.
Differential Involvement of Th1 and Th17 in Pathogenic Autoimmune Processes Triggered by Different TLR Ligands.
J. Immunol. 191: 415-23, 2013.
2)  Steinhagen F, McFarland AP, Rodriguez LG, Tewary P, Jarret A, Savan R, Klinman DM.
IRF-5 and NF-?B p50 co-regulate IFN-ß and IL-6 expression in TLR9-stimulated human plasmacytoid dendritic cells.
Eur. J. Immunol. 43: 1896-906, 2013.
3)  Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, Howard OM, Shirota H, Steinhagen F, Klinman DM, Yang D, Oppenheim JJ.
ß-Defensin 2 and 3 Promote the Uptake of Self or CpG DNA, Enhance IFN-a Production by Human Plasmacytoid Dendritic Cells, and Promote Inflammation.
J. Immunol. 191: 865-74, 2013.
4)  Bode C, Yang XP, Kiu H, Klinman DM.
Suppressive oligodeoxynucleotides promote the development of th17 cells.
PLoS ONE. 8: e67991, 2013.
5)  Kobayashi N, Hong C, Klinman DM, Shirota H.
Oligodeoxynucleotides Expressing Polyguanosine Motifs Promote Antitumor Activity through the Upregulation of IL-2.
J. Immunol. 190: 1882-9, 2013.
6)  Shimada M, Abe S, Takahashi T, Shiozaki K, Okuda M, Mizukami H, Klinman DM, Ozawa K, Okuda K.
Prophylaxis and treatment of Alzheimer"s disease by delivery of an adeno-associated virus encoding a monoclonal antibody targeting the amyloid Beta protein.
PLoS ONE. 8: e57606, 2013.
7)  Takahashi R, Sato T, Klinman DM, Shimosato T, Kaneko T, Ishigatsubo Y.
Suppressive oligodeoxynucleotides synergistically enhance antiproliferative effects of anticancer drugs in A549 human lung cancer cells.
Int. J. Oncol. 42: 429-36, 2013.
8)  Steinhagen F, Meyer C, Tross D, Gursel M, Maeda T, Klaschik S, Klinman DM.
Activation of type I interferon-dependent genes characterizes the.
J Leukoc Biol. [Epub ahead of print], 2012.
9)  Shirota H, Klinman DM.
Effect of CpG ODN on monocytic myeloid derived suppressor cells.
Oncoimmunology. 1: 780-782, 2012.
10)  Yang D, Postnikov YV, Li Y, Tewary P, de la Rosa G, Wei F, Klinman D, Gioannini T, Weiss JP, Furusawa T, Bustin M, Oppenheim JJ.
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
J. Exp. Med. 209: 157-71, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 7/18/2013.