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Y.S. Robert Cheng, D.V.M., Ph.D.

Selected Publications

1)  Cheng RY, Shang Y, Limjunyawong N, Dao T, Das S, Rabold R, Sham JS, Mitzner W, Tang WY.
Alterations of the lung methylome in allergic airway hyper-responsiveness.
Environ. Mol. Mutagen. 55: 244-55, 2014.
2)  Ridnour LA, Cheng RY, Switzer CH, Heinecke JL, Ambs S, Glynn S, Young HA, Trinchieri G, Wink DA.
Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity.
Clin. Cancer Res. 19: 1340-6, 2013.
3)  Basudhar D, Bharadwaj G, Cheng RY, Jain S, Shi S, Heinecke JL, Holland RJ, Ridnour LA, Caceres VM, Spadari-Bratfisch RC, Paolocci N, Velázquez-Martínez CA, Wink DA, Miranda KM.
Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives.
J. Med. Chem. 56: 7804-20, 2013.
4)  Switzer CH, Cheng RY, Ridnour LA, Murray MC, Tazzari V, Sparatore A, Del Soldato P, Hines HB, Glynn SA, Ambs S, Wink DA.
Dithiolethiones inhibit NF-?B activity via covalent modification in human estrogen receptor-negative breast cancer.
Cancer Res. 72: 2394-404, 2012.
5)  Switzer CH, Cheng RY, Ridnour LA, Glynn SA, Ambs S, Wink DA.
Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer.
Breast Cancer Res. 14: R125, 2012.
6)  Ridnour LA, Barasch KM, Windhausen AN, Dorsey TH, Lizardo MM, Yfantis HG, Lee DH, Switzer CH, Cheng RY, Heinecke JL, Brueggemann E, Hines HB, Khanna C, Glynn SA, Ambs S, Wink DA.
Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation.
PLoS ONE. 7: e44081, 2012.
7)  Ridnour LA, Dhanapal S, Hoos M, Wilson J, Lee J, Cheng RY, Brueggemann EE, Hines HB, Wilcock DM, Vitek MP, Wink DA, Colton CA.
Nitric oxide-mediated regulation of ß-amyloid clearance via alterations of MMP-9/TIMP-1.
J. Neurochem. 123: 736-49, 2012.
8)  Switzer CH, Glynn SA, Cheng RY, Ridnour LA, Green JE, Ambs S, Wink DA.
S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer.
Mol. Cancer Res. 10: 1203-15, 2012.
9)  Switzer CH, Glynn SA, Ridnour LA, Cheng RY, Vitek MP, Ambs S, Wink DA.
Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer.
Trends Pharmacol. Sci. 32: 644-51, 2011.
10)  Wink DA, Hines HB, Cheng RY, Switzer CH, Flores-Santana W, Vitek MP, Ridnour LA, Colton CA.
Nitric oxide and redox mechanisms in the immune response.
J. Leukoc. Biol. 89: 873-91, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 4/8/2014.