Our Science – Hughes Website
Stephen H. Hughes, Ph.D.
Selected Publications |
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| 1)
Johnson B, Metifiot M, Ferris A, Pommier Y, Hughes S. A homology model of HIV-1 integrase and analysis of mutations designed to test the model. J Mol Biol. 2013. In Press. [Journal] |
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| 2)
Metifiot M, Johnson B, Smith S, Zhao X, Marchand B, Burke T, Hughes S, Pommier Y. MK-0536 inhibits HIV-1 integrases resistant to raltegravir. Antimicrob Agents Chemother. 2013. In Press. [Journal] |
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| 3)
Das K, Arnold E, Hughes S. Lennarz W, Lane M, eds. HIV-1 reverse transcriptase structures. In: Encyclopedia of Biological Chemistry. .: Elsevier; 2013. p. 548-553 [Book Chapter] |
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| 4)
Metifiot M, Maddali K, Johnson BC, Hare S, Smith SJ, Zhao XZ, Marchand C, Burke TR, Hughes SH, Cherepanov P, Pommier Y. Activities, crystal structures, and molecular dynamics of dihydro-1H-isoindole derivatives, inhibitors of HIV-1 integrase. ACS Chem. Biol. 8: 209-17, 2013. [Journal] |
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| 5)
Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, Kewalramani VN, Hughes SH, Engelman A. Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration. J. Virol. 87: 648-58, 2013. [Journal] |
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| 6)
Lauberth SM, Nakayama T, Wu X, Ferris AL, Tang Z, Hughes SH, Roeder RG. H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation. Cell. 152: 1021-36, 2013. [Journal] |
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| 7)
Li Y, Ferris A, Lewis B, Orsulic S, Williams B, Holland E, Hughes S. Green J, Ried T, eds. The RCAS/TVA somatic gene transfer method in modeling human cancer. In: Genetically Engineered Mice for Cancer Research: Design, Analysis, Pathways, Validation and Pre-clinical Testing (Green, J.E., and Ried, T., eds,). -: Springer Publications; 2012. p. 83-112 [Book Chapter] |
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| 8)
Zhao XZ, Maddali K, Smith SJ, Métifiot M, Johnson BC, Marchand C, Hughes SH, Pommier Y, Burke TR. 6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors. Bioorg. Med. Chem. Lett. 2012. [Journal] |
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| 9)
Johnson B, Pauly G, Rai G, Patel D, Bauman J, Baker H, Das K, Schneider J, Maloney D, Arnold E, Thomas C, Hughes S. A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants. Retrovirology. 9: 99, 2012. Full Text Article. [Journal] |
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| 10)
Zhao XZ, Maddali K, Metifiot M, Smith SJ, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR. Bicyclic Hydroxy-1H-pyrrolopyridine-trione Containing HIV-1 Integrase Inhibitors. Chem Biol Drug Des. 79: 157-165, 2012. [Journal] |
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This page was last updated on 4/30/2013.
