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Our Science – Hall Website

Matthew D. Hall, Ph.D.

Selected Publications

1)  Pouliot LM, Shen DW, Suzuki T, Hall MD, Gottesman MM.
Contributions of microRNA dysregulation to cisplatin resistance in adenocarcinoma cells.
Exp. Cell Res. 319: 566-74, 2013.
2)  Shen DW, Pouliot LM, Hall MD, Gottesman MM.
Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes.
Pharmacol. Rev. 64: 706-21, 2012.
3)  Pouliot LM, Chen YC, Bai J, Guha R, Martin SE, Gottesman MM, Hall MD.
Cisplatin sensitivity mediated by WEE1 and CHK1 is mediated by miR-155 and the miR-15 family.
Cancer Res. 72: 5945-55, 2012.
4)  Pluchino KM, Hall MD, Goldsborough AS, Callaghan R, Gottesman MM.
Collateral sensitivity as a strategy against cancer multidrug resistance.
Drug Resist. Updat. 15: 98-105, 2012.
5)  Hall MD, Daly HL, Zhang JZ, Zhang M, Alderden RA, Pursche D, Foran GJ, Hambley TW.
Quantitative measurement of the reduction of platinum(IV) complexes using X-ray absorption near-edge spectroscopy (XANES).
Metallomics. 4: 568-75, 2012.
6)  Shen DW, Pouliot LM, Gillet JP, Ma W, Johnson AC, Hall MD, Gottesman MM.
The transcription factor GCF2 is an upstream repressor of the small GTPAse RhoA, regulating membrane protein trafficking, sensitivity to doxorubicin, and resistance to cisplatin.
Mol. Pharm. 9: 1822-33, 2012.
7)  Hall MD, Pike VW.
Avoiding barriers to PET radioligand development: cellular assays of brain efflux transporters.
J. Nucl. Med. 52: 338-40, 2011.
8)  Goldsborough AS, Handley MD, Dulcey AE, Pluchino KM, Kannan P, Brimacombe KR, Hall MD, Griffiths G, Gottesman MM.
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
J. Med. Chem. 54: 4987-97, 2011.
9)  Kannan P, Brimacombe KR, Kreisl WC, Liow JS, Zoghbi SS, Telu S, Zhang Y, Pike VW, Halldin C, Gottesman MM, Innis RB, Hall MD.
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET.
Proc. Natl. Acad. Sci. U.S.A. 108: 2593-8, 2011.
10)  Hall MD, Brimacombe KR, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, Fales HM, Gottesman MM.
Synthesis and structure-activity evaluation of isatin-ß-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.
J. Med. Chem. 54: 5878-89, 2011.
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This page was last updated on 3/19/2013.