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Our Science – Palena Website

Claudia M. Palena, Ph.D.

Selected Publications

1)  Palena C, Fernando RI, Hamilton DH.
An immunotherapeutic intervention against tumor progression: Targeting a driver of the epithelial-to-mesenchymal transition.
Oncoimmunology. 3: e27220, 2014.
2)  Ardiani A, Gameiro SR, Palena C, Hamilton DH, Kwilas A, King TH, Schlom J, Hodge JW.
Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process.
Cancer Res. 2014.
3)  Hamilton DH, Huang B, Fernando RI, Tsang KY, Palena C.
WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.
Cancer Res. 2014.
4)  Larocca C, Cohen JR, Fernando RI, Huang B, Hamilton DH, Palena C.
An autocrine loop between TGF-ß1 and the transcription factor Brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype.
Mol. Cancer Ther. 12: 1805-15, 2013.
5)  Hamilton DH, Litzinger MT, Jales A, Huang B, Fernando RI, Hodge JW, Ardiani A, Apelian D, Schlom J, Palena C.
Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine.
Oncotarget. 4: 1777-90, 2013.
6)  Huang B, Cohen JR, Fernando RI, Hamilton DH, Litzinger MT, Hodge JW, Palena C.
The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies.
Cell Death Dis. 4: e682, 2013.
7)  Schlom J, Hodge JW, Palena C, Greiner JW, Tsang KY, Farsaci B, Madan RA, Gulley JL.
Prendergast G, Jaffee E, eds.
Recombinant TRICOM-based therapeutic cancer vaccines: lessons learned. In: Cancer Immunotherapy: Immune Suppression and Tumor Growth. Volume Second edition.
Elsevier; 2014. In Press. [Book Chapter]
8)  Palena C, Schlom J.
Marshall J, eds.
Brachyury. In: Cancer Therapeutic Targets.
Berlin Heidelberg: Springer-Verlag; 2013. In Press. [Book Chapter]
9)  Schlom J, Palena C, Gulley JL, Greiner JW, Tsang KY, Madan RA, Hodge JW.
Lattime E, Gerson S, eds.
The use of T-cell costimulation to enhance the immunogenicity of tumors. In: Gene Therapy of Cancer: Translational Approaches from Preclinical Studies to Clinical Implementation, Third Edition. Volume Third edition.
Atlanta: Elsevier; 2013. p. 315-334 [Book Chapter]
10)  Farsaci B, Kim PS, Hodge JW, Palena C, Gulley JL, Schlom J.
Giaccone G, Soria J, eds.
Vaccine therapy and integration with other modalities. In: Targeted Therapies in Oncology. Volume Second Edition.
Boca Raton FL: CRC Press; 2013. p. 340-366 [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 3/27/2014.