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Our Science – Palena Website

Claudia M. Palena, Ph.D.

Selected Publications

1)  Fernando RI, Litzinger M, Trono P, Hamilton DH, Schlom J, Palena C.
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells.
J. Clin. Invest. 120: 533-44, 2010.
[Journal]
2)  Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C.
IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells.
Cancer Res. 71: 5296-306, 2011.
[Journal]
3)  Huang B, Cohen JR, Fernando RI, Hamilton DH, Litzinger MT, Hodge JW, Palena C.
The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies.
Cell Death Dis. 4: e682, 2013.
[Journal]
4)  Hamilton DH, Huang B, Fernando RI, Tsang K, Palena C.
WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.
Cancer Res. 74: 2510-9, 2014.
[Journal]
5)  Palena C, Roselli M, Litzinger MT, Ferroni P, Costarelli L, Spila A, Cavaliere F, Huang B, Fernando RI, Hamilton DH, Jochems C, Tsang KY, Cheng Q, Kim Lyerly H, Schlom J, Guadagni F.
Overexpression of the EMT Driver Brachyury in Breast Carcinomas: Association With Poor Prognosis.
J. Natl. Cancer Inst. 106, 2014.
[Journal]
6)  Schlom J, Hodge JW, Palena C, Greiner JW, Tsang KY, Farsaci B, Madan RA, Gulley JL.
Prendergast G, Jaffee E, eds.
Recombinant TRICOM-based therapeutic cancer vaccines: lessons learned. In: Cancer Immunotherapy: Immune Suppression and Tumor Growth. Volume Second edition.
Elsevier; 2014. In Press. [Book Chapter]
7)  Palena C, Fernando RI, Hamilton DH.
An immunotherapeutic intervention against tumor progression: Targeting a driver of the epithelial-to-mesenchymal transition.
Oncoimmunology. 3: e27220, 2014.
[Journal]
8)  Schlom J, Hodge JW, Palena C, Tsang KY, Jochems C, Greiner JW, Farsaci B, Madan RA, Heery CR, Gulley JL.
Therapeutic cancer vaccines.
Adv. Cancer Res. 121: 67-124, 2014.
[Journal]
9)  Ardiani A, Gameiro SR, Palena C, Hamilton DH, Kwilas A, King TH, Schlom J, Hodge JW.
Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process.
Cancer Res. 74: 1945-57, 2014.
[Journal]
10)  Palena C, Schlom J.
Marshall J, eds.
Brachyury. In: Cancer Therapeutic Targets.
Berlin Heidelberg: Springer-Verlag; 2013. In Press. [Book Chapter]
Click Here to View Expanded Bibliography.

This page was last updated on 6/17/2014.