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Our Science – Kotliarova Website

Svetlana Kotliarova, Ph.D.

Selected Publications

1)  Kreisl TN, Kotliarova S, Butman JA, Albert PS, Kim L, Musib L, Thornton D, Fine HA.
A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas.
Neuro-oncology. 12: 181-9, 2010.
[Journal]
2)  Kreisl TN, Kim L, Moore K, Duic P, Kotliarova S, Walling J, Musib L, Thornton D, Albert PS, Fine HA.
A phase I trial of enzastaurin in patients with recurrent gliomas.
Clin. Cancer Res. 15: 3617-23, 2009.
[Journal]
3)  Kotliarov Y, Kotliarova S, Charong N, Li A, Walling J, Aquilanti E, Ahn S, Steed ME, Su Q, Center A, Zenklusen JC, Fine HA.
Correlation analysis between single-nucleotide polymorphism and expression arrays in gliomas identifies potentially relevant target genes.
Cancer Res. 69: 1596-603, 2009.
[Journal]
4)  Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA.
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.
Cancer Cell. 13: 69-80, 2008.
[Journal]
5)  Kotliarova S, Pastorino S, Kovell LC, Kotliarov Y, Song H, Zhang W, Bailey R, Maric D, Zenklusen JC, Lee J, Fine HA.
Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation.
Cancer Res. 68: 6643-51, 2008.
[Journal]
6)  Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, Pastorino S, Purow BW, Christopher N, Zhang W, Park JK, Fine HA.
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.
Cancer Cell. 9: 391-403, 2006.
[Journal]
7)  Jana NR, Dikshit P, Goswami A, Kotliarova S, Murata S, Tanaka K, Nukina N.
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.
J. Biol. Chem. 280: 11635-40, 2005.
[Journal]
8)  Kotliarova S, Jana NR, Sakamoto N, Kurosawa M, Miyazaki H, Nekooki M, Doi H, Machida Y, Wong HK, Suzuki T, Uchikawa C, Kotliarov Y, Uchida K, Nagao Y, Nagaoka U, Tamaoka A, Oyanagi K, Oyama F, Nukina N.
Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates.
J. Neurochem. 93: 641-53, 2005.
[Journal]
9)  Bauer PO, Kotliarova SE, Matoska V, Musova Z, Hedvicakova P, Boday A, Tomek A, Nukina N, Goetz P.
Fluorescent multiplex PCR--fast method for autosomal dominant spinocerebellar ataxias screening.
Genetika. 41: 830-7, 2005.
[Journal]
10)  Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K.
Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.
Hum. Mol. Genet. 13: 1333-40, 2004.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 12/9/2011.