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Our Science – Bartesaghi Website

Alberto Bartesaghi, Ph.D.

Selected Publications

1)  Kuybeda O, Frank GA, Bartesaghi A, Borgnia M, Subramaniam S, Sapiro G.
A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography.
J. Struct. Biol. 181: 116-27, 2013.
[Journal]
2)  Milne JL, Borgnia MJ, Bartesaghi A, Tran EE, Earl LA, Schauder DM, Lengyel J, Pierson J, Patwardhan A, Subramaniam S.
Cryo-electron microscopy--a primer for the non-microscopist.
FEBS J. 280: 28-45, 2013.
[Journal]
3)  Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.
Proc. Natl. Acad. Sci. U.S.A. 110: 5921-6, 2013.
[Journal]
4)  Harris AK, Bartesaghi A, Milne JL, Subramaniam S.
HIV-1 envelope glycoprotein trimers display open quaternary conformation when bound to the gp41 membrane-proximal external-region-directed broadly neutralizing antibody Z13e1.
J. Virol. 87: 7191-6, 2013.
[Journal]
5)  Bartesaghi A, Merk A, Borgnia MJ, Milne JL, Subramaniam S.
Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy.
Nat. Struct. Mol. Biol. 20: 1352-7, 2013.
[Journal]
6)  Frank GA, Bartesaghi A, Kuybeda O, Borgnia MJ, White TA, Sapiro G, Subramaniam S.
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging.
J. Struct. Biol. 178: 165-76, 2012.
[Journal]
7)  Bartesaghi A, Lecumberry F, Sapiro G, Subramaniam S.
Protein secondary structure determination by constrained single-particle cryo-electron tomography.
Structure. 20: 2003-13, 2012.
[Journal]
8)  Tran EE, Borgnia MJ, Kuybeda O, Schauder DM, Bartesaghi A, Frank GA, Sapiro G, Milne JL, Subramaniam S.
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.
PLoS Pathog. 8: e1002797, 2012.
[Journal]
9)  Meyerson JR, White TA, Bliss D, Moran A, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Schauder D, Hartnell LM, Nandwani R, Dawood M, Kim B, Kim JH, Sununu J, Yang L, Bhatia S, Subramaniam C, Hurt DE, Gaudreault L, Subramaniam S.
Determination of molecular structures of HIV envelope glycoproteins using cryo-electron tomography and automated sub-tomogram averaging.
J Vis Exp. 2011.
[Journal]
10)  White TA, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Nandwani R, Hoxie JA, Bess JW, Lifson JD, Milne JL, Subramaniam S.
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography.
J. Virol. 85: 12114-23, 2011.
[Journal]
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This page was last updated on 6/17/2014.