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Our Science – Lee Website

KyeongEun Lee, Ph.D.

Selected Publications

1)  Lee K, KewalRamani VN.
In defense of the cell: TRIM5alpha interception of mammalian retroviruses.
Proc. Natl. Acad. Sci. U.S.A. 101: 10496-7, 2004.
2)  Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A.
The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase.
J. Virol. 84: 397-406, 2010.
3)  Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN.
Flexible use of nuclear import pathways by HIV-1.
Cell Host Microbe. 7: 221-33, 2010.
4)  Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, KewalRamani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ.
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.
PLoS Pathog. 7: e1002439, 2011.
5)  Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, Kewalramani VN.
HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6.
J. Virol. 86: 3851-60, 2012.
6)  Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN.
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.
J. Virol. 86: 4708-14, 2012.
7)  Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC.
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.
PLoS Pathog. 8: e1002896, 2012.
8)  Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Oztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, Kewalramani VN, Fassati A, Engelman A, Cherepanov P.
Structural basis for nuclear import of splicing factors by human Transportin 3.
Proc. Natl. Acad. Sci. U.S.A. 111: 2728-33, 2014.
9)  Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A.
Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.
J. Virol. 87: 648-58, 2013.
10)  Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD.
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
J. Virol. 86: 3152-66, 2012.
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This page was last updated on 3/31/2014.