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Michael J. Kruhlak, Ph.D.
|Confocal Microscopy of Apsergillus fumigatus expressing GFP|
|Confocal microscopic image depicting the branched hyphae of Aspergillus fumigatus expressing green fluorescent protein and invading the pulmonaryendothelial monolayer of the vascular compartment of an in vitro lung model. Blue structures are the nuclei of pulmonary artery endothelial cells stained with 4-6-diamidino-2-phenylindole. Galactomannan from A. fumigatus is detected as an early biomarker of invasion in the vascular compartment at the earliest microscopically apparent breach through the endothelial monolayer.|
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