Our Science – McVicar Website
Daniel W. McVicar, Ph.D.
|The McVicar Group|
|The current group includes: (Back Row) Gillian Whittaker, Laura Quigley,and Dan, and (Front Row) Sara Reynolds, Eriko Yamada, and Laurel Hughes. We have a current opening for a postdoctoral Fellow to spearhead our NK cell signaling work.|
|TLT-1 in Platelets and Megakaryocytes|
|TLT-1 (greeen)is held in the alpha granules of platelets along with p-Selectin (Red). After stimulation with Thrombin the receptors redistribute and often some TLT-1 remains within the constricted marginal band. The bottom row of images show the preformed alpha granules within in vitro derived megakaryocytes.|
|TLT-1 in Primary Megakaryocytes|
|Primary Mouse bone marrow demonstrates dramatic TLT-1 expression (green)in the alpha granules of megakaryocytes. The cells are counter stained with DAPI to demonstrate the large nucleus of the megakaryocytes and relatively small nuclei of adjacent neutrophils|
This page was last updated on 2/4/2008.