Our Science – Mackall Website
Crystal L. Mackall, M.D.
|Hua Zhang PhD, Cancer Research Training Fellow|
|Hua Zhang received medical training at the Shanghai Second Medical University in China and earned a PhD in Microbiology/Immunology at the University of Arizona in Tucson in 1995. His initial postdoctoral work focused on discovery and generation of single chain Fv molecules at the University of Maryland and then at the University of Texas. In 1998, he began to focus on T cell based therapies for cancer starting with a postdoctoral fellowship at Cedars-Sinai in Los Angeles and continuing in his current position in the Pediatric Oncology Branch which he assumed in 1999.
Hua's work focuses on human immunology and he has extensive experience in human dendritic cell culture and characterization as well as generation and maintenance of long term human T cell lines and expansion of human T cells using artificial APCs. He has a particular interest in the 4-1BB mediated costimulation for expansion of tumor reactive CTL and in the study of human CD4+CD25+ T regulatory cells.
|Martin Guimond PhD, Cancer Research Training Fellow|
|Martin Guimond received his Bachelor of Science in Microbiology (1993) and his PhD in Biomedical Sciences (2001) from the University of Montreal where he undertook graduate work focusing on transplantation biology under the direction of Dr. Denis-Claude Roy. He then undertook a postdoctoral training program at Ohio State University under the direction of Dr. Michael Caliguiri where he developed a focus on the biology of flt3 ligand as it relates to NK cell homeostasis. Dr. Guimond's joined the Mackall laboratory in April 2004 and his current focus is on the interface between T cell regeneration and host tolerance and identification of the biology of antigen presenting cell derived cytokines in T cell homeostasis. Dr. Guimond has extensive experience in mouse modeling.|
|Aviva Krauss, Clinical Fellow|
|Aviva Krauss graduated from Albert Einstein College of Medicine of Yeshiva University in 2001 and completed a Pediatric Residency at the University of Medicine and Dentistry of New Jersey/New Jersey Medical School in 2004. She is Board Certified in Pediatrics and is currently in her second year of a the Pediatric Hematology/Oncology Fellowship at Children's National Medical Center in Washington DC. Aviva will be performing the research portion of her fellowship training in the Mackall laboratory. She initiated work here in July 2005 and she plans to undertake studies of tumor immunology using mouse models, with a particular focus on pediatric solid tumors.|
This page was last updated on 9/24/2008.