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Faculty Mentors

Sankar Adhya, Ph.D. Investigator, Laboratory of Molecular Biology
Area of Interest: Regulation of gene transcription

Jairaj K Acharya, Ph.D.

Investigator, Regulation of Cell Growth Laboratory
Area of Interest: Phospholipid and sphingolipid metabolism and metabolic signaling in vivo, regulation of gene transcription

Peter D. Aplan, M.D.

Investigator, Genetics Branch
Area of Interest: Molecular mechanisms of leukemic transformation

Jonathan Ashwell, M.D.

Investigator, Laboratory of Immune Cell Biology
Area of Interest: Physiologic and pathologic regulation of apoptosis

J. Carl Barrett, Ph.D.

Investigator, Laboratory of Biosystems and Cancer
Area of Interest: Use of mouse models to study genes involved in cancer, metastasis, aging and the influence of diet, obesity and nutrition on cancer and aging

Munira A. Basrai, Ph.D.

Investigator, Genetics Branch
Area of Interest: Molecular determinants of faithful chromosome transmission and cell cycle regulation

Remy Bosselut, M.D.

Investigator, Laboratory of Immune Cell Biology
Area of Interest: Elucidating signals that mediate T lymphocyte (T cell) differentiation and survival

Geoffrey J. Clark, Ph.D.

Investigator, Cell and Cancer Biology Branch
Area of Interest: Specific small molecule antagonists of Ras oncogene action

Nancy H. Colburn, Ph.D.

Investigator, Basic Research Laboratory
Area of Interest: Gene regulation events that occur during rate-limiting phases of carcinogenesis and targeting these events for prevention

Neal G. Copeland, Ph.D.

Investigator, Mouse Cancer Genetics Program
Area of Interest: Gene knock-out and transgenic mice, genetic criteria, and cell biological approaches to understanding how genes function

William D. Figg, Pharm.D.

Investigator, Cancer Therapeutics Branch, Clinical Pharmacology Research Core, Medical Oncology Clinical Research Unit
Area of Interest: Preclinical and clinical pharmacology and experimental therapeutics

Kevin L. Gardner, M.D.,Ph.D.

Investigator, Laboratory of Pathology
Area of Interest: Mechanisms of signal transduction in activated T-cells

David Gius, M.D., Ph.D.

Investigator, Investigator, Molecular Radiation Oncology, Radiation Oncology Branch, Radiation Oncology Sciences Program
Area of Interest: Physiologic consequences of tumor cell signaling in response to oxidative stress

Adam Glick, Ph.D.

Investigator, Laboratory of Cellular Carcinogenesis and Tumor Promotion
Area of Interest: Role of TGF-beta in the pathogenesis of squamous cell cancer

Jeffrey E. Green, M.D.

Investigator, Laboratory of Cell Regulation and Carcinogenesis
Area of Interest: Transgenic models for prostate and mammary carcinogenesis
Curtis C. Harris, M.D.

Laboratory Chief, Laboratory of Human Carcinogenesis

Area of Interest Molecular genetics and molecular epidemiology of human cancer

Dennis D. Hickstein, M.D.

Investigator, Experimental Transplantation and Immunology Branch
Area of Interest: Canine model for gene therapy and stem cell tranplantation for the hematopoietic stem cell disease leukocyte adhesion deficiency; Zebrafish models of childhood leukemia and sarcoma

Wei-Shau Hu, BVM, Ph.D.

Investigator, HIV Drug Resistance Program
Area of Interest: Retrovirus replication and pathogenesis

Sonia B. Jakowlew, Ph.D.

Investigator, Cancer and Cell Biology Branch
Area of Interest: Polypeptide growth factors and their receptors in epithelial cell growth, proliferation, and cancer

Siegfried Janz, M.D.

Investigator, Laboratory of Genetics
Area of Interest: Myc-induced B cell neoplasia in mice

Jin Jen, Ph.D.

Investigator, Lab. of Population Genetics
Area of Interest: Biology and genetics of lung cancer

Seong-Jin Kim, Ph.D.

Investigator, Laboratory of Cell Regulation and Carcinogenesis
Area of Interest: Resistance to TGF-beta growth inhibitory activity during carcinogenesis

Elise C. Kohn, M.D.

Investigator, Laboratory of Pathology
Area of Interest: Molecular targets for ovarian cancer, calcium influx regulated targets, and proteomic applications

Michael R. Kuehn, Ph.D.

Investigator, Genetics Branch
Area of Interest: Basic mechanisms underlying the ordered growth, differentiation, and patterning of the mammalian embryo

Ilona Linnoila, M.D.

Investigator, Cancer & Cell Biology Branch
Area of Interest: Molecular pathology of lung carcinogenesis and differentiation

Lance Liotta, M.D., Ph.D.

Investigator, Laboratory of Pathology
Area of Interest: Molecular basis of tumor motility and invasion, clinical proteomics program, pathology residency program

Stan Lipkowitz M.D., Ph.D.

Investigator, Genetics Branch
Area of Interest: Molecular control of growth, differentiation, and death in epithelial cancer cells

Yves Pommier, M.D., Ph.D.

Investigator, Laboratory of Molecular Pharmacology
Area of Interest: DNA, topoisomerases, and HIV integrase molecular pharmacology
Karlyne M. Reilly, Ph.D Investigator, Mouse Cancer Genetics Program
Area of Interest: Using mouse models of cancer to study the biology of tumorigenesis and the genetic basis of variable susceptibility to cancer

David D. Roberts, Ph.D.

Investigator, Laboratory of Pathology
Area of Interest: Regulation of cellular function and gene expression by extracellular matrix components in tumor cells and opportunistic pathogens

Liya Shen, Ph.D.

Investigator, Laboratory of Cellular Carcinogenesis and Tumor Promotion, and Germline Mutation Core Facility (GMCF)
Area of Interest: Gene-targeting strategies to study the in vivo function of genes involved in mammalian development and establishment of animal models for human diseases

Snorri Thorgeirsson, M.D., Ph.D.

Investigator, Laboratory of Experimental Carcinogenesis
Area of Interest: Transgenic mouse models for multi-stage carcinogenesis and hepatic stem cell biology

Charles R. Vinson, Ph. D.

Investigator, Laboratory of Metabolism
Area of Interest: Gene regulation and function, the bZIP proteins

Barbara Vonderhaar, Ph.D.

Investigator, Mammary Biology & Tumorigenesis Laboratory
Area of Interest: Prolactin action in mammary gland development and tumorigenesis

Xin Wei Wang, Ph.D.

Investigator, Laboratory of Human Carcinogenesis
Area of Interest: Biology and genetics of liver cancer
Jonathan Wiest, Ph.D. Investigator, Laboratory of Cellular Carcinogenesis and Tumor
Area of Interest Genetic alterations in lung tumorigenesis

Jon M. Wigginton, M.D.

NCI-CCR Translational Research Initiative and Investigator, Pediatric Oncology Branch
Area of Interest: Antitumor mechanisms engaged by biologically-targeted strategies for the treatment of neuroblastoma and renal cell carcinoma

Berton Zbar, M.D.

Investigator, Laboratory of Immunobiology
Area of Interest: Genetic studies of inherited renal cancers-VHL diseases and heredity papillary renal carcinoma

Steven L. Zeichner, M.D., Ph.D.

Investigator, HIV and AIDS Malignancy Branch
Area of Interest: Molecular pathogenesis of HIV, herpesviruses, and related malignancies