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Structural Biophysics Laboratory (SBL)
Macromolecular NMR Section

Experimental Approach

  1. Solution NMR spectroscopy
  2. Other biophysical tools
    We routinely utilize an array of biophysical tools, available within the Structural Biophysics Laboratory and the Frederick National Lab campus whenever necessary. These tools include but not limited to mass spec, calorimeters, light scattering, ultra-centrifugation, CD and various UV- and IR spectrometers. Please see the resources of our Biophysical Resource within the SBL.
  3. Small Angle X-ray Scattering and Pulse EPR:We utilize SAXS data for examining topologies of proteins and protein:protein complexes. SBL manages access to the SAXS data collection beamline at the Argonne National Laboratory APS. This effort is overseen by Dr. Yun-Xing Wang, SBL, who is a leader in the development and application of this technology in the structural biology of RNA and proteins.
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