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Dr. Craig Thomas

Dr. Craig Thomas
Chemistry Technology

Research Summary

For more information about Chemistry Technology at NCATS, please go to:
1 - 5 of 101 results

1)  Jiang J, McCoy JG, Shen M, Leclair CA, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi W, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas CJ.
A novel class of ion displacement ligands as antagonists of the aIIbß3 receptor that limit conformational reorganization of the receptor.
Bioorg. Med. Chem. Lett. 24: 1148-53, 2014. [Journal]

2)  Thomas CJ, McKew JC.
Editorial: Playing Well with Others! Initiating and Sustaining Successful Collaborations between Industry, Academia and Government.
Curr Top Med Chem. 14: 291-3, 2014. [Journal]

3)  Shukla S, Chufan EE, Singh S, Skoumbourdis AP, Kapoor K, Boxer MB, Duveau DY, Thomas CJ, Talele TT, Ambudkar SV.
Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna(®)) with the human ABC drug transporter P-glycoprotein.
Leukemia. 28: 961-4, 2014. [Journal]

4)  Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau DY, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, Leclair CA, Rai G, Jadhav A, Peyser BD, Austin CP, Martin SE, Simeonov A, Ferrer M, Staudt LM, Thomas CJ.
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.
Proc. Natl. Acad. Sci. U.S.A. 111: 2349-54, 2014. [Journal]

5)  Duveau DY, Yasgar A, Wang Y, Hu X, Kouznetsova J, Brimacombe KR, Jadhav A, Simeonov A, Thomas CJ, Maloney DJ.
Structure-activity relationship studies and biological characterization of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Bioorg. Med. Chem. Lett. 24: 630-5, 2014. [Journal]

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