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Dr. Joel Schneider

Dr. Joel Schneider
Peptide Design and Materials

Research Summary

The Schneider group designs and characterizes novel materials for use in tissue regenerative therapy, parenteral delivery of therapeutics, delivery of cells, and antibacterial therapy. We are particularly interested in peptide and protein-based hydrogel materials formed by self-assembly mechanisms. Our work spans molecular conception, materials synthesis, nano- and bulk mechanical materials characterization, cell-material interactions, biocompatibility, and assessment of performance efficacy. Our basic research establishes how material composition and structure influences material function, and lays the foundation to ultimately translate materials to the clinic.
1 - 5 of 81 results

1)  Schneider JP.
Injectable Bioadhesive Hydrogels with Innate Antibacterial Properties.
Nature Communications. 6: in press, 2014. [Journal]

2)  Schneider JP, Pochan DJ, Ozbas B, Rajagopal K, Pakstis L, Kretsinger J.
Responsive hydrogels from the intramolecular folding and self-assembly of a designed peptide.
J. Am. Chem. Soc. 124: 15030-7, 2002. [Journal]

3)  Haines-Butterick L, Rajagopal K, Branco M, Salick D, Rughani R, Pilarz M, Lamm MS, Pochan DJ, Schneider JP.
Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells.
Proc. Natl. Acad. Sci. U.S.A. 104: 7791-6, 2007. [Journal]

4)  Sinthuvanich C, Veiga AS, Gupta K, Gaspar D, Blumenthal R, Schneider JP.
Anticancer beta-Hairpin Peptides: Membrane-Induced Folding Triggers Activity.
J. Am. Chem. Soc. 134: 6210-7, 2012. [Journal]

5)  Nagy KJ, Giano MC, Jin A, Pochan DJ, Schneider JP.
Enhanced mechanical rigidity of hydrogels formed from enantiomeric peptide assemblies.
J. Am. Chem. Soc. 133: 14975-7, 2011. [Journal]

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