DATA MANAGEMENT

CHEMISTRY PROCUREMENT SERVICE FEES

1. ChemNavigator’s Chemistry Procurement Service is available for compounds located within the iResearch Library

NIH investigators can only use the service to procure items found as a result of a specific iResearch library search. Compounds found through other sources must be procured using normal government/NIH procurement methods - this contract cannot be used as a justification for sole source if the items were not found as a result of an iResearch database search. This could also be viewed as circumventing normal NIH purchasing channels.

2. The service is not limited to screening compounds, but includes a wide range of samples including screening compounds, fine chemicals, and biochemicals.

SAMPLE PROCUREMENT

• The government shall identify the sample of interest and the supplier source.
• ChemNavigator shall use the data supplied by the government to confirm availability, price, and delivery and will provide a quote for the government’s approval.
• Upon approval of the quote, ChemNavigator shall place orders with the suppliers, receive delivery of the samples, and create a consolidated shipment to the government.
• The government shall place an order for services using the government purchase card, or by separate purchase order.
• ChemNavigator shall purchase this sample on behalf of the government
• When the supplier provides structure data, ChemNavigator shall create a consolidated registration file for the shipment. (If the supplier does not provide structure data, ChemNavigator shall only sketch the structure if the government has specifically ordered the procurement service).

DEFINITIONS AND FEE STRUCTURE

The following fees associated with the services listed below are applicable to all orders placed by NIH researchers. The cost for compounds shall be based on the quotes provided to NIH researchers from ChemNavigator. All other fees, including compound costs, shipping charges, and taxes are in addition to these fees and shall be quoted to NIH Researchers at the time the order is placed. The U.S. Government is tax-exempt. NIH Researchers are responsible for processing all actions for these services separately and determining the exact costs prior to issuing placing the order.

1. Standard Procurement Fee
   1. $15 per sample or 20% of sample cost (whichever is greater)
      Charged for each sample that ChemNavigator procures for the government for orders up to 200 samples.
   2. NOTE: For orders over 200 samples, procurement fees are quoted on a project basis.
2. Delivery in Government-Provided Vials Fee
   1. $5 per sample
      The government can elect to have samples delivered in their vials or plates. In cases where this request is made, an additional fee per sample will be applied. This fee is charged for each sample that ChemNavigator procures for the government for orders up to 200 samples.
   2. NOTE: For orders over 200 samples, delivery in Government-Provided Vial fees is quoted on a project basis.
3. Minimum Procurement Fee (Fee: $100)

   If the Standard Procurement Fee for the number of samples being procured does not exceed $100, a minimum Procurement Fee of $100 will be charged. NIH Researchers are encouraged to procure samples directly from the supplier. However, ChemNav. Procurement service allows the convenient purchase of compounds originating from multiple suppliers from any vendor around the world through the submission of a single order.

SAMPLE SOURCING (Fee $100 per hour)

ChemNavigator shall provide the government the capability to research commercial sources for a wide range of chemistry using sample structure or sample name. ChemNavigator shall use internal databases as well as external sources and suppliers. Any time the government does not specify the supplier source for a sample and requests that ChemNavigator locate a single or multiple sources for a sample, the Sourcing Fee will apply. NIH Researchers should NOT be requesting a sample that is not a result of a search in the iResearch Library. Procurement of samples shall only be made for samples identified through the iResearch Library.

After completing the sourcing process, the Sourcing Fee will be invoiced and the sourcing data provided to the government. The government can then elect whether to purchase the samples directly from the supplier sources or use ChemNavigatgor’s service to procure the samples (see Sample Procurement above).

OTHER AVAILABLE SERVICES

The following services are available if required for a specific project.

1. Sample Transfer Fee ($20 per sample)

   If the supplier cannot meet a request to provide samples in a government-provided vials or plates, ChemNavigator can arrange to have the required quantity transferred to a government-provided vial after receiving the sample. An additional fee will be charge for this service above the Procurement fee (Note: when the Sample Transfer Fee is charged, the Delivery in Government-provided Vials Fee will not be applied). The Sample Transfer Fee reflects the standard per sample rate for samples in dry powder state. This fee may vary based on sample state and overall number of samples that will be transferred. This fee applies only to samples that require transfer after shipment from the supplier.

2. Structure Research and Sketching Fee ($10 per sample)

   If neither the government nor the supplier has provided a chemical structure, and a structure is required either for sourcing or the creation of a registration file, ChemNavigator shall research and sketch the sample structure only after issuance of government purchase order or purchase card order. Any sketched structures will be charged provided to the government whether or not the sample is procured.

3. Fees Associated with Controlled Substances and Compounds Requiring Special Handling

   If ChemNavigator determines that any of the desired compounds are DEA controlled substances or require special shipping and handling (for example, toxic substances or dry ice shipments), special processes may be required to procure the compound on behalf of the government. ChemNavigator shall notify the government and provide the estimated costs as part of the quotation for the government’s approval. All orders for DEA controlled substances shall be processed by the NIH Veterinary Resources Program Pharmacy, ORS/DIRS in accordance with NIH Manual Chapter 1345 (http://vrp.od.nih.gov/pharmacy.htm). .

OTHER COSTS

1. Sample Cost (Fee: Cost of goods)

   The government will be charged the cost of goods for each sample purchased on their behalf. ChemNavigator shall work to identify the least expensive source for all samples while meeting the government’s minimum quality constraints and delivery timeframe. The government will receive, review, and approve a detailed quotation for each order prior to any order being placed and may eliminate any sample from the order prior to placing an order on the government purchase card and/or government purchase order.

2. Shipping Charges and Taxes (Fee: Based on actual charges)

   Shipping charges include all shipping charges from suppliers to ChemNavigator and from ChemNavigator to the government.

   These charges will also include any duties or VAT charges. If delivery in government-provided vials or plates is required, shipment of vials from ChemNavigator to suppliers will also be included.

PAYMENT TERMS

All payment will be made in United States dollars by separately issued orders placed on government purchase card or a separately issued purchase order.

1. ChemNavigator shall not order any samples or proceed with any project unless the government has placed the order on a government card or has issued a separate purchase order. All orders placed shall be based on firm price quote provided by ChemNavigator. Payment for all orders shall be made upon inspection and acceptance by government personnel.
2. As samples are shipped to the government, sample cost, shipping charges, and associated ChemNavigator Fees will be invoiced to the government (this includes Procurement Fees, and if applicable, the following fees: Delivery in government-provided Vial Fees, Sample Transfer Fees, and Special Handling Fees).

In addition, for credit card orders, the actual processing fee charged to ChemNavigator by VISA, MasterCard, American Express, and wire transfer fees would be invoiced to the government.