Tell CCR
"Tell CCR" about newly accepted/in press papers prior to online and print publication. Please include a copy of the manuscript in your e-mail to tellccr@mail.nih.gov
Questions may be directed to Donna Kerrigan
Our News - 2006 Scientific Advances from CCR
The twelve advances shown below were selected by CCR senior staff in response to a request from the NCI Office of Science Policy and Assessment (OSPA). OSPA will consider these advances for inclusion in the NCIšs Annual Report and as Cancer Bulletin features.
Advances in Lymphoma Research - two submissions by Louis Staudt and co-workers:
A Loss-of-Function RNA Interference Screen for Molecular Targets in Cancer
Molecular Diagnosis of Burkitt's Lymphoma
Advances in Kidney Cancer Research - submission by W. Marston Linehan:
Folliculin Encoded by the BHD Gene Interacts with a Novel Binding Protein, FNIP1,and AMPK, and Is Involved in AMPK and mTOR Signaling
Advances in Regulation of Immune Response in Cancer – submission by Crystal Mackall:
Interleukin-2 and T Cell Depletion Expand Suppressive T Cells in Humans
Advances in Development of an AIDS Vaccine - submission by Marjorie Robert-Guroff:
Replication-Competent Ad-HIV Vaccine for AIDS
Advances in AIDS-related Kaposi¹s Sarcoma - submission by Robert Yarchoan:
Interleukin-12 (IL-12) Has Clinical Activity Against AIDS-related Kaposi¹s Sarcoma
Advances in Melanoma Therapy - submission by Steve Rosenberg:
New Method of Gene Therapy Alters Immune Cells for Treatment of Advanced Melanoma
Advances in Chromosome Biology and Genomic Instability - four submissions by Andre Nussenzweig and William Bonner:
Autophosphorylation at Serine 1987 Is Dispensable for Murine Atm Activation In Vivo
Changes in Chromatin Structure and Mobility in Living Cells at Sites of DNA Double-Strand Breaks
Role of Genomic instability and p53 in AID-induced c-myc-Igh Translocations
Investigator: Andre Nussenzweig
Ionizing Radiation Induces DNA Double-Strand Breaks in Bystander Primary Human Fibroblasts
Investigator: William Bonner
Basic Science Discovery of Mechanisms of Aging - submission by Tom Misteli:
Identification of a Novel Mechanism of Human Aging
Advances in HPV Research Identification of HPV Infection Inhibitor - submission by John Schiller:
Carrageenan Is a Potent Genital HPV Infection Inhibitor
Advance in Kidney Cancer - submission by J. Carl Barrett and Joseph Riss:
Cancer as Wounds That Do Not Heal: Differences and Similarities in Renal Cell Carcinoma and Renal Tissue
Advances in Immunology Research - submission by Jay Berzofsky:
Nonclassical (Type II) NKT Cells Are Regulators of Tumor Immunosurveillance and Allow Tumor Recurrence
Advances in Stem Cell Research - submissions by Steven Hou and Snorri Thorgeirsson:
The Drosophila Homologue of the Human Tumor Suppressor Gene BHD Interacts with the JAK-STAT and TGF-beta Signaling Pathways in Regulating Male Germline Stem Cell Maintenance
Investigator: Steven Hou
Cancer Stem Cells: Subtype of Human Hepatocellular Carcinoma Derived from Hepatic Progenitor Cells
Investigator: Snorri Thorgeirsson
