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Clinical trial researches combination drug therapy for B-cell lymphoma of the central nervous system

A doctor sits at a table speaking with a patient.

Image Credit: Canva

B-cell lymphoma of the central nervous system (CNS) is a type of cancer that involves the brain or spinal cord. A clinical trial led by Mark Roschewski, M.D., Senior Clinician in the Lymphoid Malignancies Branch, is now enrolling for B-cell lymphoma of the CNS to test a combination drug therapy for the disease. The trial will take place at the NIH Clinical Center in Bethesda, Maryland, and there is no cost for participation.

For more information, please contact the NCI Medical Oncology Referral Office at (240) 760-6050 or ncimo_referrals@nih.gov

Clinicaltrials.gov identifier: NCT05211336

NCI Protocol ID: NCI000516

Official Title: Phase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid With Nivolumab (VIPOR-Nivo) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System

The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.  

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Posted on Thu, 03/30/2023