Our Science – DB Website
The Dermatology Branch conducts both clinical and basic research studying the etiology, diagnosis, and treatment of inflammatory and malignant diseases involving the skin and the host's response to these diseases. Laboratory research involves biochemical as well as biological studies of skin and is carried out in distinct, though frequently interacting, laboratories and in the clinic. Research areas of interest include characterizing skin as an immunological organ and defining the role of dendritic cells and molecules expressed by dendritic cells in the generation of skin-centered immune responses. There is significant emphasis on inflammatory skin diseases in mice and humans, and on the cutaneous microbiome in normal individuals as well as patients with atopic dermatitis and selected primary immunodeficiencies. Other investigations involve long-term clinical and laboratory studies of DNA repair, skin cancer risk and developmental abnormalities in cohorts of patients with xeroderma pigmentosum or trichothiodystrophy. The Branch laboratory research portfolio also includes studies of skin stem cells and cutaneous malignancies, including Merkel cell carcinoma.
Clinical studies conducted in the Branch involve patients with a broad range of diseases. Some studies are led by Branch investigators while others are collaborative and led by others. Observational as well as interventional studies are pursued. The Dermatology Branch Consultation Service is one of the busiest clinical services in the Clinical Research Center and is responsible for all outpatient and inpatient dermatologic patient care that is delivered at the NIH.
The Dermatology Branch also has a long tradition of being a laboratory and clinical fellowship training center for individuals who have become outstanding physician/scientists and leaders in investigative dermatology in the United States and abroad.
This page was last updated on 7/3/2014.