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Position Available in the CCR Details

Department of Health and Human Services     The NCI Center for Cancer Research is part of the National Institutes of Health (NIH), U.S. Department of Health and Human Services.

  National Institutes of Health
Position Title: Postdoctoral Fellow
Contact Name: Shalini Oberdoerffer
Contact Phone: 301-846-7104
Contact Fax: 301-846-7017
Contact E-mail: shalini.oberdoerffer@nih.gov
Branch/Laboratory/Program: Laboratory of Receptor Biology and Gene Expression
Investigator's Home Page: http://ccr.cancer.gov/staff/staff.asp?profileid=17153
Number of Positions Available: 2

Research Area Key Words:

Epigenetic regulation pre-mRNA splicing
CV Required? Yes
Number References Required: 3
Publications List Required? Yes
Position Description: A post-doctoral position is available in the RNA Processing in Cellular Development Section, to study the relationship between chromatin structure and alternative pre-mRNA splicing. The broad goal of the laboratory is to examine whether distinct chromatin signatures or DNA methylation impact splice site choice through modulation of RNA polymerase II elongation and/or splicing factor recruitment. These and related questions will be examined in primary lymphocyte cultures, both genome-wide and within the model system of developmentally-regulated CD45 alternative splicing.
Experience Required: Applicants must be strongly motivated, possess a Ph.D. or equivalent and have no more than three years of post-doctoral experience. Individuals with a background in RNA biochemistry, chromatin biology and in vitro differentiation of lymphocytes are especially encouraged to apply. Candidates with experience in bioinformatic analysis of ChIP-seq and RNA-seq data will also be considered.
Additional Information: Interested individuals should send a statement of research interests, curriculum vitae including bibliography, and contact information for three references by email to:

Dr. Shalini Oberdoerffer
RNA Processing in Cellular Development
Laboratory of Receptor Biology and Gene Regulation, CCR, NCI
Bethesda, MD
shalini.oberdoerffer@nih.gov
Location: NCI-Bethesda
   
Department of Health and Human ServicesNIH is part of the Department of Health and Human Services