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Our Science – Maldarelli Website

Frank Maldarelli, M.D., Ph.D.

Selected Publications

1)  Klase Z, Yedavalli VS, Houzet L, Perkins M, Maldarelli F, Brenchley J, Strebel K, Liu P, Jeang KT.
Activation of HIV-1 from Latent Infection via Synergy of RUNX1 Inhibitor Ro5-3335 and SAHA.
PLoS Pathog. 10: e1003997, 2014.
[Journal]
2)  De Ravin SS, Gray JT, Throm RE, Spindler J, Kearney M, Wu X, Coffin JM, Hughes SH, Malderelli F, Sorrentino BP, Malech HL.
False-Positive HIV PCR Test Following Ex Vivo Lentiviral Gene Transfer Treatment of X-linked Severe Combined Immunodeficiency Vector.
Mol. Ther. 22: 244-5, 2014.
[Journal]
3)  Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O'Shea A, Rehm C, Poethke C, Kovacs N, Mellors JW, Coffin JM, Maldarelli F.
Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy.
PLoS Pathog. 10: e1004010, 2014.
[Journal]
4)  Shao W, Kearney MF, Boltz VF, Spindler JE, Mellors JW, Maldarelli F, Coffin JM.
PAPNC, A novel method to calculate nucleotide diversity from large scale next generation sequencing data.
J. Virol. Methods. 2014.
[Journal]
5)  Lau CY, Maldarelli F, Eckelman WC, Neumann RD.
Rational development of radiopharmaceuticals for HIV-1.
Nucl. Med. Biol. 41: 299-308, 2014.
[Journal]
6)  Maldarelli F, Kearney M, Palmer S, Stephens R, Mican J, Polis MA, Davey RT, Kovacs J, Shao W, Rock-Kress D, Metcalf JA, Rehm C, Greer SE, Lucey DL, Danley K, Alter H, Mellors JW, Coffin JM.
HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion.
J. Virol. 87: 10313-23, 2013.
[Journal]
7)  McMahon D, Jones J, Wiegand A, Gange SJ, Kearney M, Palmer S, McNulty S, Metcalf JA, Acosta E, Rehm C, Coffin JM, Mellors JW, Maldarelli F.
Short-Course Raltegravir Intensification Does Not Reduce Persistent Low-Level Viremia in Patients with HIV-1 Suppression during Receipt of Combination Antiretroviral Therapy.
Clin Infect Dis. 50: 912-919, 2010.
[Journal]
8)  Josefsson L, Palmer S, Faria NR, Lemey P, Casazza J, Ambrozak D, Kearney M, Shao W, Kottilil S, Sneller M, Mellors J, Coffin JM, Maldarelli F.
Single Cell Analysis of Lymph Node Tissue from HIV-1 Infected Patients Reveals that the Majority of CD4(+) T-cells Contain One HIV-1 DNA Molecule.
PLoS Pathog. 9: e1003432, 2013.
[Journal]
9)  Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O'Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW, Siliciano RF, Maldarelli F.
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.
Proc. Natl. Acad. Sci. U.S.A. 106: 9403-8, 2009.
[Journal]
10)  Maldarelli F, Palmer S, King MS, Wiegand A, Polis MA, Mican J, Kovacs JA, Davey RT, Rock-Kress D, Dewar R, Liu S, Metcalf JA, Rehm C, Brun SC, Hanna GJ, Kempf DJ, Coffin JM, Mellors JW.
ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy Viremia.
PLoS Pathog. 3: e46, 2007.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 4/2/2014.