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Our Science – Waldmann Website

Thomas A. Waldmann, M.D.

Selected Publications

1)  Uchiyama T, Broder S, Waldmann TA.
A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.
J. Immunol. 126: 1393-7, 1981.
2)  Burton JD, Bamford RN, Peters C, Grant AJ, Kurys G, Goldman CK, Brennan J, Roessler E, Waldmann TA.
A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
Proc. Natl. Acad. Sci. U.S.A. 91: 4935-9, 1994.
3)  Waldmann TA.
The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design.
Nat. Rev. Immunol. 6: 595-601, 2006.
4)  Waldmann TA, Lugli E, Roederer M, Perera LP, Smedley JV, Macallister RP, Goldman CK, Bryant BR, Decker JM, Fleisher TA, Lane HC, Sneller MC, Kurlander RJ, Kleiner DE, Pletcher JM, Figg WD, Yovandich JL, Creekmore SP.
Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques.
Blood. 117: 4787-95, 2011.
5)  Ju W, Zhang M, Jiang JK, Thomas CJ, Oh U, Bryant BR, Chen J, Sato N, Tagaya Y, Morris JC, Janik JE, Jacobson S, Waldmann TA.
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP.
Blood. 117: 1938-46, 2011.
6)  Nguyen VP, Chen J, Petrus MN, Goldman CK, Kruhlak MJ, Bamford RN, Waldmann TA.
A New Domain in the Toll/IL-1R Domain-Containing Adaptor Inducing Interferon-ß Factor Protein Amino Terminus Is Important for Tumor Necrosis Factor-a Receptor-Associated Factor 3 Association, Protein Stabilization and Interferon Signaling.
J Innate Immun. 6: 377-93, 2014.
7)  Ju W, Zhang M, Petrus M, Maeda M, Pise-Masison CA, Waldmann TA.
Combination of 9-aminoacridine with Campath-1H provides effective therapy for a murine model of adult T-cell leukemia.
Retrovirology. 11: 43, 2014.
8)  Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, Waldmann TA, Peiris JS, Perera LP, Poon LL.
IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection.
Proc. Natl. Acad. Sci. U.S.A. 111: 5676-81, 2014.
9)  Morris JC, Ramlogan-Steel CA, Yu P, Black BA, Mannan P, Allison JP, Waldmann TA, Steel JC.
Vaccination with tumor cells expressing IL-15 and IL-15Ra inhibits murine breast and prostate cancer.
Gene Ther. 21: 393-401, 2014.
10)  Bellon M, Ko NL, Lee MJ, Yao Y, Waldmann TA, Trepel JB, Nicot C.
Adult T-cell leukemia cells overexpress Wnt5a and promote osteoclast differentiation.
Blood. 121: 5045-54, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 6/30/2014.