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Our Science – Carrington Website

Mary N. Carrington, Ph.D.

Selected Publications

1)  Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H.
Association of HLA-DRB1-restricted CD4? T cell responses with HIV immune control.
Nat. Med. 19: 930-3, 2013.
[Journal]
2)  McLaren PJ, Coulonges C, Ripke S, van den Berg L, Buchbinder S, Carrington M, Cossarizza A, Dalmau J, Deeks SG, Delaneau O, De Luca A, Goedert JJ, Haas D, Herbeck JT, Kathiresan S, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, O'Brien SJ, Pereyra F, Plummer FA, Poli G, Qi Y, Rucart P, Sandhu MS, Shea PR, Schuitemaker H, Theodorou I, Vannberg F, Veldink J, Walker BD, Weintrob A, Winkler CA, Wolinsky S, Telenti A, Goldstein DB, de Bakker PI, Zagury JF, Fellay J.
Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls.
PLoS Pathog. 9: e1003515, 2013.
[Journal]
3)  Salie M, van der Merwe L, Möller M, Daya M, van der Spuy G, van Helden PD, Martin MP, Gao XJ, Warren R, Carrington M, Hoal EG.
Associations between Human HLA Class-I Variants and the Mycobacterium tuberculosis Subtypes Causing Disease.
J. Infect. Dis. 2013.
[Journal]
4)  Martin MP, Carrington M.
Immunogenetics of HIV disease.
Immunol. Rev. 254: 245-64, 2013.
[Journal]
5)  Kuniholm MH, Anastos K, Kovacs A, Gao X, Marti D, Sette A, Greenblatt RM, Peters M, Cohen MH, Minkoff H, Gange SJ, Thio CL, Young MA, Xue X, Carrington M, Strickler HD.
Relation of HLA class I and II supertypes with spontaneous clearance of hepatitis C virus.
Genes Immun. 14: 330-5, 2013.
[Journal]
6)  Janes H, Friedrich DP, Krambrink A, Smith RJ, Kallas EG, Horton H, Casimiro DR, Carrington M, Geraghty DE, Gilbert PB, McElrath MJ, Frahm N.
Vaccine-Induced Gag-Specific T Cells Are Associated With Reduced Viremia After HIV-1 Infection.
J. Infect. Dis. 2013.
[Journal]
7)  Apps R, Qi Y, Carlson JM, Chen H, Gao X, Thomas R, Yuki Y, Del Prete GQ, Goulder P, Brumme ZL, Brumme CJ, John M, Mallal S, Nelson G, Bosch R, Heckerman D, Stein JL, Soderberg KA, Moody MA, Denny TN, Zeng X, Fang J, Moffett A, Lifson JD, Goedert JJ, Buchbinder S, Kirk GD, Fellay J, McLaren P, Deeks SG, Pereyra F, Walker B, Michael NL, Weintrob A, Wolinsky S, Liao W, Carrington M.
Influence of HLA-C Expression Level on HIV Control.
Science. 340: 87-91, 2013.
[Journal]
8)  Thomas R, Thio CL, Apps R, Qi Y, Gao X, Marti D, Stein JL, Soderberg KA, Moody MA, Goedert JJ, Kirk GD, Hoots WK, Wolinsky S, Carrington M.
A novel variant marking HLA-DP Expression Levels Predicts Hepatitis B Virus Recovery.
J Virol. [Epub ahead of print], 2012.
[Journal]
9)  Carrington M, Walker BD.
Immunogenetics of spontaneous control of HIV.
Annu. Rev. Med. 63: 131-45, 2012.
[Journal]
10)  O'huigin C, Kulkarni S, Xu Y, Deng Z, Kidd J, Kidd K, Gao X, Carrington M.
The molecular origin and consequences of escape from miRNA regulation by HLA-C alleles.
Am. J. Hum. Genet. 89: 424-31, 2011.
[Journal]
11)  Kuniholm MH, Gao X, Xue X, Kovacs A, Marti D, Thio CL, Peters MG, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Young MA, Strickler HD, Carrington M.
The relation of HLA genotype to hepatitis C viral load and markers of liver fibrosis in HIV-infected and HIV-uninfected women.
J. Infect. Dis. 203: 1807-14, 2011.
[Journal]
12)  Alter A, Huong NT, Singh M, Orlova M, Van Thuc N, Katoch K, Gao X, Thai VH, Ba NN, Carrington M, Abel L, Mehra N, Alcaïs A, Schurr E.
Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India.
J. Infect. Dis. 203: 1274-81, 2011.
[Journal]
13)  Bashirova AA, Thomas R, Carrington M.
HLA/KIR restraint of HIV: surviving the fittest.
Annu. Rev. Immunol. 29: 295-317, 2011.
[Journal]
14)  Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M.
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Science. 330: 1551-7, 2010.
[Journal]
15)  Hiby SE, Apps R, Sharkey AM, Farrell LE, Gardner L, Mulder A, Claas FH, Walker JJ, Redman CW, Redman CC, Morgan L, Tower C, Regan L, Moore GE, Carrington M, Moffett A.
Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.
J. Clin. Invest. 120: 4102-10, 2010.
[Journal]
16)  Wang SS, Abdou AM, Morton LM, Thomas R, Cerhan JR, Gao X, Cozen W, Rothman N, Davis S, Severson RK, Bernstein L, Hartge P, Carrington M.
Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology.
Blood. 115: 4820-3, 2010.
[Journal]
17)  Lane J, McLaren PJ, Dorrell L, Shianna KV, Stemke A, Pelak K, Moore S, Oldenburg J, Alvarez-Roman MT, Angelillo-Scherrer A, Boehlen F, Bolton-Maggs PH, Brand B, Brown D, Chiang E, Cid-Haro AR, Clotet B, Collins P, Colombo S, Dalmau J, Fogarty P, Giangrande P, Gringeri A, Iyer R, Katsarou O, Kempton C, Kuriakose P, Lin J, Makris M, Manco-Johnson M, Tsakiris DA, Martinez-Picado J, Mauser-Bunschoten E, Neff A, Oka S, Oyesiku L, Parra R, Peter-Salonen K, Powell J, Recht M, Shapiro A, Stine K, Talks K, Telenti A, Wilde J, Yee TT, Wolinsky SM, Martinson J, Hussain SK, Bream JH, Jacobson LP, Carrington M, Goedert JJ, Haynes BF, McMichael AJ, Goldstein DB, Fellay J.
A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.
Hum. Mol. Genet. 22: 1903-10, 2013.
[Journal]
18)  Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E.
F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.
Haemophilia. 19: 113-8, 2013.
[Journal]
19)  Duggal P, Thio CL, Wojcik GL, Goedert JJ, Mangia A, Latanich R, Kim AY, Lauer GM, Chung RT, Peters MG, Kirk GD, Mehta SH, Cox AL, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Tobler LH, Busch MP, Alexander G, Rosen HR, Gao X, Abdel-Hamid M, Apps R, Carrington M, Thomas DL.
Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts.
Ann. Intern. Med. 158: 235-45, 2013.
[Journal]
20)  Shea PR, Shianna KV, Carrington M, Goldstein DB.
Host genetics of HIV acquisition and viral control.
Annu. Rev. Med. 64: 203-17, 2013.
[Journal]
21)  Azzoni L, Foulkes AS, Papasavvas E, Mexas AM, Lynn KM, Mounzer K, Tebas P, Jacobson JM, Frank I, Busch MP, Deeks SG, Carrington M, O'Doherty U, Kostman J, Montaner LJ.
Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration.
J. Infect. Dis. 207: 213-22, 2013.
[Journal]
22)  Pyo CW, Wang R, Vu Q, Cereb N, Yang SY, Duh FM, Wolinsky S, Martin MP, Carrington M, Geraghty DE.
Recombinant structures expand and contract inter and intragenic diversification at the KIR locus.
BMC Genomics. 14: 89, 2013.
[Journal]
23)  Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G.
Altered distribution of mucosal NK cells during HIV infection.
Mucosal Immunol. 5: 30-40, 2012.
[Journal]
24)  Li JZ, Brumme CJ, Lederman MM, Brumme ZL, Wang H, Spritzler J, Carrington M, Medvik K, Walker BD, Schooley RT, Kuritzkes DR.
Characteristics and Outcomes of Initial Virologic Suppressors during Analytic Treatment Interruption in a Therapeutic HIV-1 gag Vaccine Trial.
PloS one. 7: e34134, 2012.
[Journal]
25)  Deng Z, Gao X, Kirk G, Wolinsky S, Carrington M.
Characterization of the HLA-C(*)07:01:01G allele group in European and African-American cohorts.
Hum Immunol. [Epub ahead of print], 2012.
[Journal]
26)  Carlson JM, Brumme CJ, Martin E, Listgarten J, Brockman MA, Le AQ, Chui CK, Cotton LA, Knapp DJ, Riddler SA, Haubrich R, Nelson G, Pfeifer N, Deziel CE, Heckerman D, Apps R, Carrington M, Mallal S, Harrigan PR, John M, Brumme ZL.
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.
J. Virol. 86: 13202-16, 2012.
[Journal]
27)  Thobakgale CF, Fadda L, Lane K, Toth I, Pereyra F, Bazner S, Ndung'u T, Walker BD, Rosenberg E, Alter G, Carrington M, Allen T, Altfeld M.
Frequent and Strong Antibody-Mediated Natural Killer Cell Activation to HIV-1 Env in Individuals with Chronic HIV-1 Infection.
J Virol. [Epub ahead of print], 2012.
[Journal]
28)  Kløverpris HN, Harndahl M, Leslie AJ, Carlson JM, Ismail N, van der Stok M, Huang KH, Chen F, Riddell L, Steyn D, Goedhals D, van Vuuren C, Frater J, Walker BD, Carrington M, Ndung'u T, Buus S, Goulder P.
HIV control through a single nucleotide on the HLA-B locus.
J. Virol. 86: 11493-500, 2012.
[Journal]
29)  Naruto T, Gatanaga H, Nelson G, Sakai K, Carrington M, Oka S, Takiguchi M.
HLA class I mediated control of HIV-1 in Japanese, where the protective HLA-B*57 and -B*27 are absent.
J Virol. 86:: 10870-2, 2012.
[Journal]
30)  Fadda L, Körner C, Kumar S, van Teijlingen NH, Piechocka-Trocha A, Carrington M, Altfeld M.
HLA-Cw*0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function.
PLoS Pathog. 8: e1002805, 2012.
[Journal]
31)  Tomescu C, Duh FM, Hoh R, Viviani A, Harvill K, Martin MP, Carrington M, Deeks SG, Montaner LJ.
Impact of protective killer inhibitory receptor/human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers.
AIDS. 26: 1869-78, 2012.
[Journal]
32)  Carrington M, Alter G.
Innate Immune Control of HIV.
Cold Spring Harb Perspect Med. 2: a007070, 2012.
[Journal]
33)  Chen H, Hayashi G, Lai OY, Dilthey A, Kuebler PJ, Wong TV, Martin MP, Fernandez Vina MA, McVean G, Wabl M, Leslie KS, Maurer T, Martin JN, Deeks SG, Carrington M, Bowcock AM, Nixon DF, Liao W.
Psoriasis Patients Are Enriched for Genetic Variants That Protect against HIV-1 Disease.
PLoS Genet. 8: e1002514, 2012.
[Journal]
34)  Tang M, Lautenberger JA, Gao X, Sezgin E, Hendrickson SL, Troyer JL, David VA, Guan L, McIntosh CE, Guo X, Zheng Y, Liao J, Deng H, Malasky M, Kessing B, Winkler CA, Carrington M, Dé The G, Zeng Y, O'Brien SJ.
The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove.
PLoS Genet. 8: e1003103, 2012.
[Journal]
35)  O'Connor GM, Yamada E, Rampersaud A, Thomas R, Carrington M, McVicar DW.
Analysis of Binding of KIR3DS1*014 to HLA Suggests Distinct Evolutionary History of KIR3DS1.
J. Immunol. 187: 2162-71, 2011.
[Journal]
36)  Fadda L, O'Connor G, Kumar S, Trocha A, Gardiner C, Carrington M, McVicar D, Altfeld M.
Common HIV-1 peptide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules.
J Virol. 85: 5970-4, 2011.
[Journal]
37)  Pelak K, Need AC, Fellay J, Shianna KV, Feng S, Urban TJ, Ge D, De Luca A, Martinez-Picado J, Wolinsky SM, Martinson JJ, Jamieson BD, Bream JH, Martin MP, Borrow P, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Carrington M, Goldstein DB, Alter G.
Copy number variation of KIR genes influences HIV-1 control.
PLoS Biol. 9: e1001208, 2011.
[Journal]
38)  Kulkarni S, Savan R, Qi Y, Gao X, Yuki Y, Bass SE, Martin MP, Hunt P, Deeks SG, Telenti A, Pereyra F, Goldstein D, Wolinsky S, Walker B, Young HA, Carrington M.
Differential microRNA regulation of HLA-C expression and its association with HIV control.
Nature. 472: 495-8, 2011.
[Journal]
39)  Augusto DG, Zehnder-Alves L, Pincerati MR, Martin MP, Carrington M, Petzl-Erler ML.
Diversity of the KIR gene cluster in an urban Brazilian population.
Immunogenetics. 64: 143-52, 2011.
[Journal]
40)  Li JZ, Brumme ZL, Brumme CJ, Wang H, Spritzler J, Robertson MN, Lederman MM, Carrington M, Walker BD, Schooley RT, Kuritzkes DR.
Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial.
J. Infect. Dis. 203: 976-83, 2011.
[Journal]
41)  Dahirel V, Shekhar K, Pereyra F, Miura T, Artyomov M, Talsania S, Allen TM, Altfeld M, Carrington M, Irvine DJ, Walker BD, Chakraborty AK.
From the Cover: Coordinate linkage of HIV evolution reveals regions of immunological vulnerability.
Proc. Natl. Acad. Sci. U.S.A. 108: 11530-5, 2011.
[Journal]
42)  Alter G, Heckerman D, Schneidewind A, Fadda L, Kadie CM, Carlson JM, Oniangue-Ndza C, Martin M, Li B, Khakoo SI, Carrington M, Allen TM, Altfeld M.
HIV-1 adaptation to NK-cell-mediated immune pressure.
Nature. 476: 96-100, 2011.
[Journal]
43)  McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperavičiūtė D, Carrington M, Sills GJ, Marson T, Jia X, de Bakker PI, Chinthapalli K, Molokhia M, Johnson MR, O'Connor GD, Chaila E, Alhusaini S, Shianna KV, Radtke RA, Heinzen EL, Walley N, Pandolfo M, Pichler W, Park BK, Depondt C, Sisodiya SM, Goldstein DB, Deloukas P, Delanty N, Cavalleri GL, Pirmohamed M.
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
N. Engl. J. Med. 364: 1134-43, 2011.
[Journal]
44)  Matthews PC, Adland E, Listgarten J, Leslie A, Mkhwanazi N, Carlson JM, Harndahl M, Stryhn A, Payne RP, Ogwu A, Huang KH, Frater J, Paioni P, Kloverpris H, Jooste P, Goedhals D, van Vuuren C, Steyn D, Riddell L, Chen F, Luzzi G, Balachandran T, Ndung'u T, Buus S, Carrington M, Shapiro R, Heckerman D, Goulder PJ.
HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.
J. Immunol. 186: 5675-86, 2011.
[Journal]
45)  Kuniholm MH, Gao X, Xue X, Kovacs A, Anastos K, Marti D, Greenblatt RM, Cohen MH, Minkoff H, Gange SJ, Fazzari M, Young MA, Strickler HD, Carrington M.
Human Leukocyte Antigen (HLA) Genotype and Risk of HIV Disease Progression Before and After Initiation of Antiretroviral Therapy.
J Virol. 85: 10826-33, 2011.
[Journal]
46)  Colantonio AD, Bimber BN, Neidermyer WJ, Reeves RK, Alter G, Altfeld M, Johnson RP, Carrington M, O'Connor DH, Evans DT.
KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif.
PLoS Pathog. 7: e1001316, 2011.
[Journal]
47)  Seich Al Basatena NK, Macnamara A, Vine AM, Thio CL, Astemborski J, Usuku K, Osame M, Kirk GD, Donfield SM, Goedert JJ, Bangham CR, Carrington M, Khakoo SI, Asquith B.
KIR2DL2 enhances protective and detrimental HLA class I-mediated immunity in chronic viral infection.
PLoS Pathog. 7: e1002270, 2011.
[Journal]
48)  Erlich RL, Jia X, Anderson S, Banks E, Gao X, Carrington M, Gupta N, DePristo MA, Henn MR, Lennon NJ, de Bakker PI.
Next-generation sequencing for HLA typing of class I loci.
BMC Genomics. 12: 42, 2011.
[Journal]
49)  Chang J, Lindsay RJ, Kulkarni S, Lifson JD, Carrington M, Altfeld M.
Polymorphisms in interferon regulatory factor 7 reduce interferon-α responses of plasmacytoid dendritic cells to HIV-1.
AIDS. 25: 715-7, 2011.
[Journal]
50)  Julg B, Moodley ES, Qi Y, Ramduth D, Reddy S, Mncube Z, Gao X, Goulder PJ, Detels R, Ndung'u T, Walker BD, Carrington M.
Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.
J. Infect. Dis. 203: 803-9, 2011.
[Journal]
51)  Kim AY, Kuntzen T, Timm J, Nolan BE, Baca MA, Reyor LL, Berical AC, Feller AJ, Johnson KL, Schulze zur Wiesch J, Robbins GK, Chung RT, Walker BD, Carrington M, Allen TM, Lauer GM.
Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.
Gastroenterology. 140: 686-696.e1, 2011.
[Journal]
52)  Abi-Rached L, Jobin MJ, Kulkarni S, McWhinnie A, Dalva K, Gragert L, Babrzadeh F, Gharizadeh B, Luo M, Plummer FA, Kimani J, Carrington M, Middleton D, Rajalingam R, Beksac M, Marsh SG, Maiers M, Guethlein LA, Tavoularis S, Little AM, Green RE, Norman PJ, Parham P.
The shaping of modern human immune systems by multiregional admixture with archaic humans.
Science. 334: 89-94, 2011.
[Journal]
53)  Wong AH, Williams K, Reddy S, Wilson D, Giddy J, Alter G, Ghebremichael M, Carrington MN, Ndung'u T, Walker BD, Altfeld M, Carr WH.
Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults.
AIDS Res. Hum. Retroviruses. 26: 459-69, 2010.
[Journal]
54)  Specht A, Telenti A, Martinez R, Fellay J, Bailes E, Evans DT, Carrington M, Hahn BH, Goldstein DB, Kirchhoff F.
Counteraction of HLA-C-mediated immune control of HIV-1 by Nef.
J. Virol. 84: 7300-11, 2010.
[Journal]
55)  Lederman MM, Alter G, Daskalakis DC, Rodriguez B, Sieg SF, Hardy G, Cho M, Anthony D, Harding C, Weinberg A, Silverman RH, Douek DC, Margolis L, Goldstein DB, Carrington M, Goedert JJ.
Determinants of protection among HIV‐exposed seronegative persons: an overview.
J. Infect. Dis. 202 Suppl 3: S333-8, 2010.
[Journal]
56)  Conesa A, Fernández-Mestre M, Padrón D, Toro F, Silva N, Tassinari P, Blanca I, Martin MP, Carrington M, Layrisse Z.
Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.
Tissue Antigens. 75: 724-9, 2010.
[Journal]
57)  Hiby SE, Ashrafian-Bonab M, Farrell L, Single RM, Balloux F, Carrington M, Moffett A, Ebrahimi Z.
Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.
Immunogenetics. 62: 65-73, 2010.
[Journal]
58)  Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, Deeks SG, Pereyra F, Carrington M, Walker BD, Chakraborty AK.
Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection.
Nature. 465: 350-4, 2010.
[Journal]
59)  Julg B, Williams KL, Reddy S, Bishop K, Qi Y, Carrington M, Goulder PJ, Ndung'u T, Walker BD.
Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses.
J. Virol. 84: 5540-9, 2010.
[Journal]
60)  Tang M, Zeng Y, Poisson A, Marti D, Guan L, Zheng Y, Deng H, Liao J, Guo X, Sun S, Nelson G, de Thé G, Winkler CA, O'Brien SJ, Carrington M, Gao X.
Haplotype-dependent HLA susceptibility to nasopharyngeal carcinoma in a Southern Chinese population.
Genes Immun. 11: 334-42, 2010.
[Journal]
61)  Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, Kewalramani VN.
HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN).
J. Biol. Chem. 285: 2100-12, 2010.
[Journal]
62)  Gao X, O'Brien TR, Welzel TM, Marti D, Qi Y, Goedert JJ, Phair J, Pfeiffer R, Carrington M.
HLA-B alleles associate consistently with HIV heterosexual transmission, viral load, and progression to AIDS, but not susceptibility to infection.
AIDS. 24: 1835-40, 2010.
[Journal]
63)  Martin MP, Borecki IB, Zhang Z, Nguyen L, Ma D, Gao X, Qi Y, Carrington M, Rader JS.
HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer.
Immunogenetics. 62: 761-5, 2010.
[Journal]
64)  Pelak K, Goldstein DB, Walley NM, Fellay J, Ge D, Shianna KV, Gumbs C, Gao X, Maia JM, Cronin KD, Hussain SK, Carrington M, Michael NL, Weintrob AC.
Host determinants of HIV-1 control in African Americans.
J. Infect. Dis. 201: 1141-9, 2010.
[Journal]
65)  Abdou AM, Gao X, Cozen W, Cerhan JR, Rothman N, Martin MP, Davis S, Schenk M, Chanock SJ, Hartge P, Carrington M, Wang SS.
Human leukocyte antigen (HLA) A1-B8-DR3 (8.1) haplotype, tumor necrosis factor (TNF) G-308A, and risk of non-Hodgkin lymphoma.
Leukemia. 24: 1055-8, 2010.
[Journal]
66)  Martin MP, Qi Y, Goedert JJ, Hussain SK, Kirk GD, Hoots WK, Buchbinder S, Carrington M, Thio CL.
IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection.
J. Infect. Dis. 202: 1749-53, 2010.
[Journal]
67)  Tomescu C, Duh FM, Lanier MA, Kapalko A, Mounzer KC, Martin MP, Carrington M, Metzger DS, Montaner LJ.
Increased plasmacytoid dendritic cell maturation and natural killer cell activation in HIV-1 exposed, uninfected intra-venous drug users.
AIDS (London, England). 2010.
[Journal]
68)  Yindom LM, Leligdowicz A, Martin MP, Gao X, Qi Y, Zaman SM, van der Loeff MS, van Tienen C, Jaye A, Aveika A, Worwui A, Diatta M, Vincent T, Whittle HC, Rowland-Jones SL, Walton R, Carrington M.
Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.
J. Virol. 84: 8202-8, 2010.
[Journal]
69)  Kulkarni S, Martin MP, Carrington M.
KIR genotyping by multiplex PCR-SSP.
Methods Mol. Biol. 612: 365-75, 2010.
[Journal]
70)  Mackelprang RD, Carrington M, John-Stewart G, Lohman-Payne B, Richardson BA, Wamalwa D, Gao X, Majiwa M, Mbori-Ngacha D, Farquhar C.
Maternal human leukocyte antigen A*2301 is associated with increased mother-to-child HIV-1 transmission.
J. Infect. Dis. 202: 1273-7, 2010.
[Journal]
71)  Traherne JA, Martin M, Ward R, Ohashi M, Pellett F, Gladman D, Middleton D, Carrington M, Trowsdale J.
Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.
Hum. Mol. Genet. 19: 737-51, 2010.
[Journal]
72)  O'Connor SL, Lhost JJ, Becker EA, Detmer AM, Johnson RC, Macnair CE, Wiseman RW, Karl JA, Greene JM, Burwitz BJ, Bimber BN, Lank SM, Tuscher JJ, Mee ET, Rose NJ, Desrosiers RC, Hughes AL, Friedrich TC, Carrington M, O'Connor DH.
MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques.
Sci Transl Med. 2: 22ra18, 2010.
[Journal]
73)  Kuniholm MH, Kovacs A, Gao X, Xue X, Marti D, Thio CL, Peters MG, Terrault NA, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Harris TG, Young MA, Strickler HD, Carrington M.
Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia.
Hepatology. 51: 1514-22, 2010.
[Journal]
74)  Averdam A, Petersen B, Rosner C, Neff J, Roos C, Eberle M, Aujard F, Munch C, Schempp W, Carrington M, Shiina T, Inoko H, Knaust F, Coggill P, Sehra H, Beck S, Abi-Rached L, Reinhardt R, Walter L.
A novel system of polymorphic and diverse NK cell receptors in primates.
PLoS Genet. 5: e1000688, 2009.
[Journal]
75)  Torimiro JN, Javanbakht H, Diaz-Griffero F, Kim J, Carr JK, Carrington M, Sawitzke J, Burke DS, Wolfe ND, Dean M, Sodroski J.
A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies.
Virology. 391: 140-7, 2009.
[Journal]
76)  Thammavongsa V, Schaefer M, Filzen T, Collins KL, Carrington M, Bangia N, Raghavan M.
Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503.
Immunogenetics. 61: 703-16, 2009.
[Journal]
77)  Yu KJ, Gao X, Chen CJ, Yang XR, Diehl SR, Goldstein A, Hsu WL, Liang XS, Marti D, Liu MY, Chen JY, Carrington M, Hildesheim A.
Association of human leukocyte antigens with nasopharyngeal carcinoma in high-risk multiplex families in Taiwan.
Hum. Immunol. 2009.
[Journal]
78)  Urban TJ, Weintrob AC, Fellay J, Colombo S, Shianna KV, Gumbs C, Rotger M, Pelak K, Dang KK, Detels R, Martinson JJ, O'Brien SJ, Letvin NL, McMichael AJ, Haynes BF, Carrington M, Telenti A, Michael NL, Goldstein DB.
CCL3L1 and HIV/AIDS susceptibility.
Nat. Med. 15: 1110-2, 2009.
[Journal]
79)  Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, Urban TJ, Zhang K, Gumbs CE, Smith JP, Castagna A, Cozzi-Lepri A, De Luca A, Easterbrook P, Günthard HF, Mallal S, Mussini C, Dalmau J, Martinez-Picado J, Miro JM, Obel N, Wolinsky SM, Martinson JJ, Detels R, Margolick JB, Jacobson LP, Descombes P, Antonarakis SE, Beckmann JS, O'Brien SJ, Letvin NL, McMichael AJ, Haynes BF, Carrington M, Feng S, Telenti A, Goldstein DB.
Common genetic variation and the control of HIV-1 in humans.
PLoS Genet. 5: e1000791, 2009.
[Journal]
80)  Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Donfield SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M.
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.
Nature. 461: 798-801, 2009.
[Journal]
81)  Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M.
HIV-1-specific CD8+ T cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells.
J. Virol. 2009.
[Journal]
82)  Alter G, Rihn S, Walter K, Nolting A, Martin M, Rosenberg ES, Miller JS, Carrington M, Altfeld M.
HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.
J. Virol. 83: 6798-805, 2009.
[Journal]
83)  Duda A, Lee-Turner L, Fox J, Robinson N, Dustan S, Kaye S, Fryer H, Carrington M, McClure M, McLean AR, Fidler S, Weber J, Phillips RE, Frater AJ.
HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection.
J. Virol. 83: 1228-39, 2009.
[Journal]
84)  Huang J, Goedert JJ, Sundberg EJ, Cung TD, Burke PS, Martin MP, Preiss L, Lifson J, Lichterfeld M, Carrington M, Yu XG.
HLA-B*35-Px-mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses.
J. Exp. Med. 206: 2959-66, 2009.
[Journal]
85)  Thomas R, Apps R, Qi Y, Gao X, Male V, O'hUigin C, O'Connor G, Ge D, Fellay J, Martin JN, Margolick J, Goedert JJ, Buchbinder S, Kirk GD, Martin MP, Telenti A, Deeks SG, Walker BD, Goldstein D, McVicar DW, Moffett A, Carrington M.
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.
Nat. Genet. 41: 1290-4, 2009.
[Journal]
86)  Brumme Z, Wang B, Nair K, Brumme C, de Pierres C, Reddy S, Julg B, Moodley E, Thobakgale C, Lu Z, van der Stok M, Bishop K, Mncube Z, Chonco F, Yuki Y, Frahm N, Brander C, Carrington M, Freedberg K, Kiepiela P, Goulder P, Walker B, Ndung'u T, Losina E.
Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa.
Clin. Infect. Dis. 49: 956-64, 2009.
[Journal]
87)  Julg B, Reddy S, van der Stok M, Kulkarni S, Qi Y, Bass S, Gold B, Nalls MA, Nelson GW, Walker BD, Carrington M, Ndung'u T.
Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population.
Cell Host Microbe. 5: 413-5; author reply 418-9, 2009.
[Journal]
88)  Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, Goodman R, Schneidewind A, Power KA, Toth I, Frahm N, Alter G, Brander C, Carrington M, Walker BD, Altfeld M, Heckerman D, Allen TM.
Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.
J. Virol. 83: 1845-55, 2009.
[Journal]
89)  Meier A, Chang JJ, Chan ES, Pollard RB, Sidhu HK, Kulkarni S, Wen TF, Lindsay RJ, Orellana L, Mildvan D, Bazner S, Streeck H, Alter G, Lifson JD, Carrington M, Bosch RJ, Robbins GK, Altfeld M.
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.
Nat. Med. 15: 955-9, 2009.
[Journal]
90)  Walley NM, Julg B, Dickson SP, Fellay J, Ge D, Walker BD, Carrington M, Cohen MS, de Bakker PI, Goldstein DB, Shianna KV, Haynes BF, Letvin NL, McMichael AJ, Michael NL, Weintrob AC.
The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression.
Cell Host Microbe. 5: 408-10; author reply 418-9, 2009.
[Journal]
91)  Welzel TM, Morgan TR, Bonkovsky HL, Naishadham D, Pfeiffer RM, Wright EC, Hutchinson AA, Crenshaw AT, Bashirova A, Carrington M, Dotrang M, Sterling RK, Lindsay KL, Fontana RJ, Lee WM, Di Bisceglie AM, Ghany MG, Gretch DR, Chanock SJ, Chung RT, O'Brien TR.
Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
Hepatology. 49: 1847-58, 2009.
[Journal]
92)  Hiby SE, Regan L, Lo W, Farrell L, Carrington M, Moffett A.
Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage.
Hum. Reprod. 23: 972-6, 2008.
[Journal]
93)  Kulkarni S, Single RM, Martin MP, Rajalingam R, Badwe R, Joshi N, Carrington M.
Comparison of the rapidly evolving KIR locus in Parsis and natives of India.
Immunogenetics. 60: 121-9, 2008.
[Journal]
94)  Ahlenstiel G, Martin MP, Gao X, Carrington M, Rehermann B.
Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses.
J. Clin. Invest. 118: 1017-26, 2008.
[Journal]
95)  Prada N, Davis B, Jean-Pierre P, Roche ML, Duh FM, Carrington M, Poles M, Mehandru S, Mohri H, Markowitz M.
Drug-Susceptible HIV-1 Infection Despite Intermittent Fixed-Dose Combination Tenofovir/Emtricitabine as Prophylaxis Is Associated With Low-Level Viremia, Delayed Seroconversion, and an Attenuated Clinical Course.
J. Acquir. Immune Defic. Syndr. 49: 117-22, 2008.
[Journal]
96)  Li H, Pascal V, Martin MP, Carrington M, Anderson SK.
Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.
PLoS Genet. 4: e1000254, 2008.
[Journal]
97)  Mizukoshi E, Eisenbach C, Edlin BR, Newton KP, Raghuraman S, Weiler-Normann C, Tobler LH, Busch MP, Carrington M, McKeating JA, O'Brien TR, Rehermann B.
Hepatitis C virus (HCV)-specific immune responses of long-term injection drug users frequently exposed to HCV.
J. Infect. Dis. 198: 203-12, 2008.
[Journal]
98)  Hunt PW, Carrington M.
Host genetic determinants of HIV pathogenesis: an immunologic perspective.
Curr Opin HIV AIDS. 3: 342-8, 2008.
[Journal]
99)  Thio CL, Astemborski J, Thomas R, Mosbruger T, Witt MD, Goedert JJ, Hoots K, Winkler C, Thomas DL, Carrington M.
Interaction between RANTES promoter variant and CCR5Delta32 favors recovery from hepatitis B.
J. Immunol. 181: 7944-7, 2008.
[Journal]
100)  Martin MP, Single RM, Wilson MJ, Trowsdale J, Carrington M.
KIR haplotypes defined by segregation analysis in 59 Centre d'Etude Polymorphisme Humain (CEPH) families.
Immunogenetics. 60: 767-74, 2008.
[Journal]
101)  Martin M, Single R, Wilson M, Trowsdale J, Carrington M.
KIR haplotypes defined by segregation analysis in 59 Centre d’Etude Polymorphisme Humain (CEPH) families.
Immunogenetics. In Press, 2008.
[Journal]
102)  Martin MP, Carrington M.
KIR locus polymorphisms: genotyping and disease association analysis.
Methods Mol. Biol. 415: 49-64, 2008.
[Journal]
103)  Carrington M, Martin MP, van Bergen J.
KIR-HLA intercourse in HIV disease.
Trends Microbiol. 16: 620-7, 2008.
[Journal]
104)  Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD.
Marked epitope and allele-specific differences in rates of mutation in HIV-1 Gag, Pol and Nef CTL epitopes in acute/early HIV-1 infection.
J. Virol. Epub ahead of print, 2008.
[Journal]
105)  Mackelprang RD, John-Stewart G, Carrington M, Richardson B, Rowland-Jones S, Gao X, Mbori-Ngacha D, Mabuka J, Lohman-Payne B, Farquhar C.
Maternal HLA homozygosity and mother-child HLA concordance increase the risk of vertical transmission of HIV-1.
J. Infect. Dis. 197: 1156-61, 2008.
[Journal]
106)  Single RM, Martin MP, Meyer D, Gao X, Carrington M.
Methods for assessing gene content diversity of KIR with examples from a global set of populations.
Immunogenetics. 2008.
[Journal]
107)  Thomas R, Yamada E, Alter G, Martin MP, Bashirova AA, Norman PJ, Altfeld M, Parham P, Anderson SK, McVicar DW, Carrington M.
Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation?.
J. Immunol. 180: 6743-50, 2008.
[Journal]
108)  Listgarten J, Brumme Z, Kadie C, Xiaojiang G, Walker B, Carrington M, Goulder P, Heckerman D.
Statistical resolution of ambiguous HLA typing data.
PLoS Comput. Biol. 4: e1000016, 2008.
[Journal]
109)  Ortiz M, Kaessmann H, Zhang K, Bashirova A, Carrington M, Quintana-Murci L, Telenti A.
The evolutionary history of the CD209 (DC-SIGN) family in humans and non-human primates.
Genes Immun. Epub ahead of print, 2008.
[Journal]
110)  Giraldo-Vela JP, Rudersdorf R, Chung C, Qi Y, Wallace LT, Bimber B, Borchardt GJ, Fisk DL, Glidden CE, Loffredo JT, Piaskowski SM, Furlott JR, Morales-Martinez JP, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI.
The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllers.
J. Virol. 82: 859-70, 2008.
[Journal]
111)  Kulkarni S, Martin MP, Carrington M.
The Yin and Yang of HLA and KIR in human disease.
Semin. Immunol. Epub ahead of print, 2008.
[Journal]
112)  Martin MP, Pascal V, Yeager M, Phair J, Kirk GD, Hoots K, O'Brien SJ, Anderson SK, Carrington M.
A mutation in KIR3DS1 that results in truncation and lack of cell surface expression.
Immunogenetics. 59: 823-9, 2007.
[Journal]
113)  Mehandru S, Vcelar B, Wrin T, Stiegler G, Joos B, Mohri H, Boden D, Galovich J, Tenner-Racz K, Racz P, Carrington M, Petropoulos C, Katinger H, Markowitz M.
Adjunctive passive immunotherapy in HIV-1-infected individuals treated with antiviral therapy during acute/early infection.
J Virol. 81: 11016-31, 2007.
[Journal]
114)  Thananchai H, Gillespie G, Martin MP, Bashirova A, Yawata N, Yawata M, Easterbrook P, McVicar DW, Maenaka K, Parham P, Carrington M, Dong T, Rowland-Jones S.
Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B.
J. Immunol. 178: 33-7, 2007.
[Journal]
115)  Bozzacco L, Trumpfheller C, Siegal FP, Mehandru S, Markowitz M, Carrington M, Nussenzweig MC, Piperno AG, Steinman RM.
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes.
Proc. Natl. Acad. Sci. U.S.A. 104: 1289-94, 2007.
[Journal]
116)  Pascal V, Yamada E, Martin MP, Alter G, Altfeld M, Metcalf JA, Baseler MW, Adelsberger JW, Carrington M, Anderson SK, McVicar DW.
Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection.
J. Immunol. 179: 1625-33, 2007.
[Journal]
117)  Alter G, Martin MP, Teigen N, Carr WH, Suscovich TJ, Schneidewind A, Streeck H, Waring M, Meier A, Brander C, Lifson JD, Allen TM, Carrington M, Altfeld M.
Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes.
J. Exp. Med. 204: 3027-36, 2007.
[Journal]
118)  Yu KJ, Bashirova A, Madeleine MM, Cheng J, Johnson LG, Schwartz SM, Carrington M, Hildesheim A.
Evaluation of the association with cervical cancer of polymorphisms in syndecan-1, a heparan sulfate proteoglycan involved with viral cell entry.
Cancer Epidemiol. Biomarkers Prev. 16: 2504-8, 2007.
[Journal]
119)  Torimiro JN, Wolfe ND, Thomas A, Martin MP, Mpoudi-Ngole E, Tamoufe U, Birx DL, Carrington M, Burke DS, Carr JK.
Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon.
AIDS. 21: 527-8, 2007.
[Journal]
120)  Thio CL, Astemborski J, Bashirova A, Mosbruger T, Greer S, Witt MD, Goedert JJ, Hilgartner M, Majeske A, O'Brien SJ, Thomas DL, Carrington M.
Genetic protection against hepatitis B virus conferred by CCR5Delta32: Evidence that CCR5 contributes to viral persistence.
J. Virol. 81: 441-5, 2007.
[Journal]
121)  Single RM, Martin MP, Gao X, Meyer D, Yeager M, Kidd JR, Kidd KK, Carrington M.
Global diversity and evidence for coevolution of KIR and HLA.
Nat Genet. 39: 1114-9, 2007.
[Journal]
122)  Welzel TM, Gao X, Pfeiffer RM, Martin MP, O'Brien SJ, Goedert JJ, Carrington M, O'Brien TR.
HLA-B Bw4 alleles and HIV-1 transmission in heterosexual couples.
AIDS. 21: 225-9, 2007.
[Journal]
123)  Martin MP, Qi Y, Gao X, Yamada E, Martin JN, Pereyra F, Colombo S, Brown EE, Shupert WL, Phair J, Goedert JJ, Buchbinder S, Kirk GD, Telenti A, Connors M, O'Brien SJ, Walker BD, Parham P, Deeks SG, McVicar DW, Carrington M.
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.
Nat. Genet. 39: 733-40, 2007.
[Journal]
124)  Gillespie GM, Bashirova A, Dong T, McVicar DW, Rowland-Jones SL, Carrington M.
Lack of KIR3DS1 binding to MHC class I Bw4 tetramers in complex with CD8+ T cell epitopes.
AIDS Res. Hum. Retroviruses. 23: 451-5, 2007.
[Journal]
125)  Loffredo JT, Maxwell J, Qi Y, Glidden CE, Borchardt GJ, Soma T, Bean AT, Beal DR, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI.
Mamu-B*08-positive macaques control simian immunodeficiency virus replication.
J. Virol. 81: 8827-32, 2007.
[Journal]
126)  Marzi A, Mitchell DA, Chaipan C, Fisch T, Doms RW, Carrington M, Desrosiers RC, Pohlmann S.
Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin.
Virology. 368: 322-30, 2007.
[Journal]
127)  Spierings E, Hendriks M, Absi L, Canossi A, Chhaya S, Crowley J, Dolstra H, Eliaou JF, Ellis T, Enczmann J, Fasano ME, Gervais T, Gorodezky C, Kircher B, Laurin D, Leffell MS, Loiseau P, Malkki M, Markiewicz M, Martinetti M, Maruya E, Mehra N, Oguz F, Oudshoorn M, Pereira N, Rani R, Sergeant R, Thomson J, Tran TH, Turpeinen H, Yang KL, Zunec R, Carrington M, de Knijff P, Goulmy E.
Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations.
PLoS Genet. 3: e103, 2007.
[Journal]
128)  Goedert JJ, Li HC, Gao XJ, Chatterjee N, Sonoda S, Biggar RJ, Cranston B, Kim N, Carrington M, Morgan O, Hanchard B, Hisada M.
Risk of human T-lymphotropic virus type I-associated diseases in Jamaica with common HLA types.
Int. J. Cancer. 121: 1092-7, 2007.
[Journal]
129)  de Bakker PI, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, Ke X, Monsuur AJ, Whittaker P, Delgado M, Morrison J, Richardson A, Walsh EC, Gao X, Galver L, Hart J, Hafler DA, Pericak-Vance M, Todd JA, Daly MJ, Trowsdale J, Wijmenga C, Vyse TJ, Beck S, Murray SS, Carrington M, Gregory S, Deloukas P, Rioux JD.
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.
Nat Genet. 38: 1166-72, 2006.
[Journal]
130)  Barsov EV, Andersen H, Coalter VJ, Carrington M, Lifson JD, Ott DE.
Capture of antigen-specific T lymphocytes from human blood by selective immortalization to establish long-term T-cell lines maintaining primary cell characteristics.
Immunol. Lett. 105: 26-37, 2006.
[Journal]
131)  Bashirova AA, Bleiber G, Qi Y, Hutcheson H, Yamashita T, Johnson RC, Cheng J, Alter G, Goedert JJ, Buchbinder S, Hoots K, Vlahov D, May M, Maldarelli F, Jacobson L, O'brien SJ, Telenti A, Carrington M.
Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1.
J. Virol. 80: 6757-63, 2006.
[Journal]
132)  Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C.
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Nat. Immunol. 7: 173-8, 2006.
[Journal]
133)  Gao X, Single RM, Karacki P, Marti D, O'Brien SJ, Carrington M.
Diversity of MICA and linkage disequilibrium with HLA-B in two North American populations.
Hum. Immunol. 67: 152-8, 2006.
[Journal]
134)  Traherne JA, Horton R, Roberts AN, Miretti MM, Hurles ME, Stewart CA, Ashurst JL, Atrazhev AM, Coggill P, Palmer S, Almeida J, Sims S, Wilming LG, Rogers J, de Jong PJ, Carrington M, Elliott JF, Sawcer S, Todd JA, Trowsdale J, Beck S.
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLoS Genet. 2: e9, 2006.
[Journal]
135)  Torimiro JN, Carr JK, Wolfe ND, Karacki P, Martin MP, Gao X, Tamoufe U, Thomas A, Ngole EM, Birx DL, McCutchan FE, Burke DS, Carrington M.
HLA class I diversity among rural rainforest inhabitants in Cameroon: identification of A*2612-B*4407 haplotype.
Tissue Antigens. 67: 30-7, 2006.
[Journal]
136)  Sambrook JG, Bashirova A, Andersen H, Piatak M, Vernikos GS, Coggill P, Lifson JD, Carrington M, Beck S.
Identification of the ancestral killer immunoglobulin-like receptor gene in primates.
BMC Genomics. 7: 209, 2006.
[Journal]
137)  O'Hanlon TP, Carrick DM, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Blackshear PJ, Plotz PH, Love LA, Miller FW.
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.
Medicine (Baltimore). 85: 111-27, 2006.
[Journal]
138)  Streeck H, Jessen H, Alter G, Teigen N, Waring MT, Jessen A, Stahmer I, Lunzen J, Lichterfeld M, Gao X, Allen TM, Carrington M, Walker BD, Rockstroh JK, Altfeld M.
Immunological and Virological Impact of Highly Active Antiretroviral Therapy Initiated during Acute HIV-1 Infection.
J. Infect. Dis. 194: 734-9, 2006.
[Journal]
139)  Qi Y, Martin MP, Gao X, Jacobson L, Goedert JJ, Buchbinder S, Kirk GD, O'brien SJ, Trowsdale J, Carrington M.
KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections.
PLoS Pathog. 2, 2006.
[Journal]
140)  Moffett A, Hiby S, Carrington M.
Letter in response to article by Saito et al.
J. Reprod. Immunol. 71: 132-3, 2006.
[Journal]
141)  Martin M, Carrington M.
Natural killer cells and HIV-1 disease.
Current Opinion in HIV and AIDS. 1: 226-231, 2006.
[Journal]
142)  Liu H, Carrington M, Wang C, Holte S, Lee J, Greene B, Hladik F, Koelle DM, Wald A, Kurosawa K, Rinaldo CR, Celum C, Detels R, Corey L, McElrath MJ, Zhu T.
Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility.
J. Infect. Dis. 193: 698-702, 2006.
[Journal]
143)  Yant LJ, Friedrich TC, Johnson RC, May GE, Maness NJ, Enz AM, Lifson JD, O'Connor DH, Carrington M, Watkins DI.
The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication.
J. Virol. 80: 5074-7, 2006.
[Journal]
144)  Carrington M, Martin MP.
The impact of variation at the KIR gene cluster on human disease.
Curr. Top. Microbiol. Immunol. 298: 225-57, 2006.
[Journal]
145)  Bashirova AA, Martin MP, McVicar DW, Carrington M.
The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense.
Annu Rev Genomics Hum Genet. 7: 277-300, 2006.
[Journal]
146)  Carrington M.
Antiviral synergism.
Nat Genet. 37: 565-6, 2005.
[Journal]
147)  Carrington M, Wang S, Martin MP, Gao X, Schiffman M, Cheng J, Herrero R, Rodriguez AC, Kurman R, Mortel R, Schwartz P, Glass A, Hildesheim A.
Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci.
J. Exp. Med. 201: 1069-75, 2005.
[Journal]
148)  Martin MP, Carrington M.
Immunogenetics of viral infections.
Curr. Opin. Immunol. 17: 510-6, 2005.
[Journal]
149)  Malkki M, Single R, Carrington M, Thomson G, Petersdorf E.
MHC microsatellite diversity and linkage disequilibrium among common HLA-A, HLA-B, DRB1 haplotypes: implications for unrelated donor hematopoietic transplantation and disease association studies.
Tissue Antigens. 66: 114-24, 2005.
[Journal]
150)  Sambrook JG, Bashirova A, Palmer S, Sims S, Trowsdale J, Abi-Rached L, Parham P, Carrington M, Beck S.
Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates.
Genome Res. 15: 25-35, 2005.
[Journal]
151)  Dong H, Wigmore K, Carrington MN, Dean M, Turpin JA, Howard OM.
Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.
Genes Immun. 6: 6609-19, 2005.
[Journal]
152)  Andersen H, Rossio JL, Coalter V, Poore B, Martin MP, Carrington M, Lifson JD.
Characterization of rhesus macaque natural killer activity against a rhesus-derived target cell line at the single-cell level.
Cell Immunol. 231: 85-95, 2004.
[Journal]
153)  Hiby SE, Walker JJ, O'shaughnessy KM, Redman CW, Carrington M, Trowsdale J, Moffett A.
Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success.
J. Exp. Med. 200: 957-65, 2004.
[Journal]
154)  Nelson GW, Martin MP, Gladman D, Wade J, Trowsdale J, Carrington M.
Cutting edge: Heterozygote advantage in autoimmune disease: Hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in Psoriatic Arthritis.
J. Immunol. 173: 4273-6, 2004.
[Journal]
155)  Martin MP, Lederman MM, Hutcheson HB, Goedert JJ, Nelson GW, van Kooyk Y, Detels R, Buchbinder S, Hoots K, Vlahov D, O'Brien SJ, Carrington M.
DC-SIGN promoter polymorphism: Association with increased risk for parenteral, but not mucosal acquisition of HIV-1 infection.
J Virol. 78: 14053-6, 2004.
[Journal]
156)  Winkler CA, Hendel H, Carrington M, Smith MW, Nelson GW, O'brien SJ, Phair J, Vlahov D, Jacobson LP, Rappaport J, Vasilescu A, Bertin-Maghit S, An P, Lu W, Andrieu J, Schachter F, Therwath A, Zagury J.
Dominant Effects of CCR2-CCR5 Haplotypes in HIV-1 Disease Progression.
J Acquir Immune Defic Syndr. 37: 1534-1538, 2004.
[Journal]
157)  Khakoo SI, Thio CL, Martin MP, Brooks CR, Gao X, Astemborski J, Cheng J, Goedert JJ, Vlahov D, Hilgartner M, Cox S, Little AM, Alexander GJ, Cramp ME, O'Brien SJ, Rosenberg WM, Thomas DL, Carrington M.
HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection.
Science. 305: 872-4, 2004.
[Journal]
158)  Gourraud PA, Mano S, Barnetche T, Carrington M, Inoko H, Cambon-Thomsen A.
Integration of microsatellite characteristics in the MHC region: a literature and sequence based analysis.
Tissue Antigens. 64: 543-55, 2004.
[Journal]
159)  Carrington M, Cullen M.
Justified chauvinism: advances in defining meiotic recombination through sperm typing.
Trends Genet. 20: 196-205, 2004.
[Journal]
160)  Liu C, Carrington M, Kaslow RA, Gao X, Rinaldo CR, Jacobson LP, Margolick JB, Phair J, O'Brien SJ, Detels R.
Lack of associations between HLA Class II Alleles and Resistance to HIV-1 Infection Among White, Non-Hispanic Homosexual Men.
J. Acquir. Immune. Defic. Syndr. 37: 1313-1317, 2004.
[Journal]
161)  Karacki PS, Gao X, Thio CL, Thomas DL, Goedert JJ, Vlahov D, Kaslow RA, Strathdee S, Hilgartner MW, O'Brien SJ, Carrington M.
MICA and recovery from hepatitis C virus and hepatitis B virus infections.
Genes Immun. 5: 261-6, 2004.
[Journal]
162)  Maloney EM, Nagai M, Hisada M, Soldan SS, Goebel PB, Carrington M, Sawada T, Brennan MB, Cranston B, Hanchard B, Jacobson S.
Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia.
J. Infect. Dis. 189: 41-5, 2004.
[Journal]
163)  Wu L, Martin TD, Carrington M, KewalRamani VN.
Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission.
Virology. 318: 17-23, 2004.
[Journal]
164)  Walsh EC, Mather KA, Schaffner SF, Farwell L, Daly MJ, Patterson N, Cullen M, Carrington M, Bugawan TL, Erlich H, Campbell J, Barrett J, Miller K, Thomson G, Lander ES, Rioux JD.
An integrated haplotype map of the human major histocompatibility complex.
Am J Hum Genet. 73: 580-90, 2003.
[Journal]
165)  Liu C, Carrington M, Kaslow RA, Gao X, Rinaldo CR, Jacobson LP, Margolick JB, Phair J, O'Brien SJ, Detels R.
Association of polymorphisms in human leukocyte antigen class I and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infection.
J. Infect. Dis. 187: 1404-10, 2003.
[Journal]
166)  Thio CL, Thomas DL, Karacki P, Gao X, Marti D, Kaslow RA, Goedert JJ, Hilgartner M, Strathdee SA, Duggal P, O'Brien SJ, Astemborski J, Carrington M.
Comprehensive analysis of class I and class II HLA antigens and chronic hepatitis B virus infection.
J. Virol. 77: 12083-7, 2003.
[Journal]
167)  Martin MP, Bashirova A, Traherne J, Trowsdale J, Carrington M.
Cutting Edge: Expansion of the KIR locus by unequal crossing over.
J. Immunol. 171: 2192-5, 2003.
[Journal]
168)  Chan HW, Kurago ZB, Stewart CA, Wilson MJ, Martin MP, Mace BE, Carrington M, Trowsdale J, Lutz CT.
DNA methylation maintains allele-specific KIR gene expression in human natural killer cells.
J. Exp. Med. 197: 245-55, 2003.
[Journal]
169)  Cullen M, Malasky M, Harding A, Carrington M.
High-density map of short tandem repeats across the human major histocompatibility complex.
Immunogenetics. 54: 900-10, 2003.
[Journal]
170)  Carrington M.
HLA microsatellite analysis.
Methods Mol Biol. 210: 325-32, 2003.
[Journal]
171)  Marsh SG, Parham P, Dupont B, Geraghty DE, Trowsdale J, Middleton D, Vilches C, Carrington M, Witt C, Guethlein LA, Shilling H, Garcia CA, Hsu KC, Wain H.
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.
Tissue Antigens. 62: 79-86, 2003.
[Journal]
172)  Marsh SG, Parham P, Dupont B, Geraghty DE, Trowsdale J, Middleton D, Vilches C, Carrington M, Witt C, Guethlein LA, Shilling H, Garcia CA, Hsu KC, Wain H.
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.
Immunogenetics. 55: 220-6, 2003.
[Journal]
173)  Marsh SG, Parham P, Dupont B, Geraghty DE, Trowsdale J, Middleton D, Vilches C, Carrington M, Witt C, Guethlein LA, Shilling H, Garcia CA, Hsu KC, Wain H.
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.
Eur. J. Immunogenet. 30: 229-34, 2003.
[Journal]
174)  Marsh SG, Parham P, Dupont B, Geraghty DE, Trowsdale J, Middleton D, Vilches C, Carrington M, Witt C, Guethlein LA, Shilling H, Garcia CA, Hsu KC, Wain H.
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.
Hum. Immunol. 64: 648-54, 2003.
[Journal]
175)  Bashirova AA, Wu L, Cheng J, Martin TD, Martin MP, Benveniste RE, Lifson JD, KewalRamani VN, Hughes A, Carrington M.
Novel member of the CD209 (DC-SIGN) gene family in primates.
J. Virol. 77: 217-27, 2003.
[Journal]
176)  Carrington M, O'Brien SJ.
The influence of HLA genotype on AIDS.
Annu. Rev. Med. 54: 535-51, 2003.
[Journal]
177)  Zhang M, Schmid S, Carrington M, O'Brien TR.
Antibodies to varicella-zoster virus in blood donors with genetic variance in CC chemokine receptor 5.
Lancet. 359: 1034-6, 2002.
[Journal]
178)  Dean M, Carrington M, O'Brien SJ.
Balanced polymorphism selected by genetic versus infectious human disease.
Annu Rev Genomics Hum Genet. 3: 263-92, 2002.
[Journal]
179)  Hisada M, Lal RB, Masciotra S, Rudolph DL, Martin MP, Carrington M, Wilks RJ, Manns A.
Chemokine receptor gene polymorphisms and risk of human T lymphotropic virus type I infection in Jamaica.
J Infect Dis. 185: 1351-4, 2002.
[Journal]
180)  Wang SS, Hildesheim A, Gao X, Schiffman M, Herrero R, Bratti MC, Sherman ME, Barnes WA, Greenberg MD, McGowan L, Mortel R, Schwartz PE, Zaino RJ, Glass AG, Burk RD, Karacki P, Carrington M.
Comprehensive analysis of human leukocyte antigen class I alleles and cervical neoplasia in 3 epidemiologic studies.
J Infect Dis. 186: 598-605, 2002.
[Journal]
181)  Martin MP, Nelson G, Lee JH, Pellett F, Gao X, Wade J, Wilson MJ, Trowsdale J, Gladman D, Carrington M.
Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles.
J Immunol. 169: 2818-22, 2002.
[Journal]
182)  Carrington M, Bontrop RE.
Effects of MHC class I on HIV/SIV disease in primates.
AIDS. 16 Suppl 4: S105-14, 2002.
[Journal]
183)  Martin MP, Gao X, Lee JH, Nelson GW, Detels R, Goedert JJ, Buchbinder S, Hoots K, Vlahov D, Trowsdale J, Wilson M, O'Brien SJ, Carrington M.
Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS.
Nat Genet. 31: 429-34, 2002.
[Journal]
184)  Cullen M, Perfetto SP, Klitz W, Nelson G, Carrington M.
High-resolution patterns of meiotic recombination across the human major histocompatibility complex.
Am J Hum Genet. 71: 759-76, 2002.
[Journal]
185)  Sheppard HW, Celum C, Michael NL, O'Brien S, Dean M, Carrington M, Dondero D, Buchbinder SP.
HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion.
J Acquir Immune Defic Syndr. 29: 307-13, 2002.
[Journal]
186)  Thio CL, Gao X, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Astemborski J, Carrington M, Thomas DL.
HLA-Cw*04 and hepatitis C virus persistence.
J Virol. 76: 4792-7, 2002.
[Journal]
187)  Jin X, Gao X, Ramanathan M, Deschenes GR, Nelson GW, O'Brien SJ, Goedert JJ, Ho DD, O'Brien TR, Carrington M.
Human immunodeficiency virus type 1 (HIV-1)-specific CD8+-T-cell responses for groups of HIV-1-infected individuals with different HLA-B*35 genotypes.
J Virol. 76: 12603-10, 2002.
[Journal]
188)  Wang SS, Hildesheim A, Gao X, Schiffman M, Herrero R, Bratti MC, Sherman ME, Barnes WA, Greenberg MD, McGowan L, Mortel R, Schwartz PE, Zaino RJ, Glass AG, Burk RD, Karacki P, Carrington M.
Human leukocyte antigen class I alleles and cervical neoplasia: no heterozygote advantage.
Cancer Epidemiol. Biomarkers Prev. 11: 419-20, 2002.
[Journal]
189)  Yang OO, Boscardin WJ, Matud J, Hausner MA, Hultin LE, Hultin PM, Shih R, Ferbas J, Siegal FP, Shodell M, Shearer GM, Grene E, Carrington M, O'Brien S, Price CB, Detels R, Jamieson BD, Giorgi JV.
Immunologic profile of highly exposed yet HIV type 1-seronegative men.
AIDS Res. Hum. Retroviruses. 18: 1051-65, 2002.
[Journal]
190)  Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN.
Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.
Proc Natl Acad Sci U S A. 99: 1568-73, 2002.
[Journal]
191)  Bashirova AA, Geijtenbeek TB, van Duijnhoven GC, van Vliet SJ, Eilering JB, Martin MP, Wu L, Martin TD, Viebig N, Knolle PA, KewalRamani VN, van Kooyk Y, Carrington M.
A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.
J Exp Med. 193: 671-8, 2001.
[Journal]
192)  Carrington M, Nelson G, O'Brien SJ.
Considering genetic profiles in functional studies of immune responsiveness to HIV-1.
Immunol Lett. 79: 131-40, 2001.
[Journal]
193)  Gao X, Nelson GW, Karacki P, Martin MP, Phair J, Kaslow R, Goedert JJ, Buchbinder S, Hoots K, Vlahov D, O'Brien SJ, Carrington M.
Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS.
N Engl J Med. 344: 1668-75, 2001.
[Journal]
194)  O'Brien SJ, Gao X, Carrington M.
HLA and AIDS: a cautionary tale.
Trends Mol Med. 7: 379-81, 2001.
[Journal]
195)  Wang SS, Wheeler CM, Hildesheim A, Schiffman M, Herrero R, Bratti MC, Sherman ME, Alfaro M, Hutchinson ML, Morales J, Lorincz A, Burk RD, Carrington M, Erlich HA, Apple RJ.
Human leukocyte antigen class I and II alleles and risk of cervical neoplasia: results from a population-based study in Costa Rica.
J Infect Dis. 184: 1310-4, 2001.
[Journal]
196)  Esser MT, Bess JW, Suryanarayana K, Chertova E, Marti D, Carrington M, Arthur LO, Lifson JD.
Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1.
J. Virol. 75: 1152-64, 2001.
[Journal]
197)  Thio CL, Thomas DL, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Marti D, Astemborski J, Carrington M.
Racial differences in HLA class II associations with hepatitis C virus outcomes.
J Infect Dis. 184: 16-21, 2001.
[Journal]
198)  El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Rabkin CS.
The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer.
Nature. 412: 99, 2001.
[Journal]
199)  Thio CL, Thomas DL, Carrington M.
Chronic viral hepatitis and the human genome.
Hepatology. 31: 819-27, 2000.
[Journal]
200)  Yeager M, Carrington M, Hughes AL.
Class I and class II MHC bind self peptide sets that are strikingly different in their evolutionary characteristics.
Immunogenetics. 51: 8-15, 2000.
[Journal]
201)  O'Brien TR, McDermott DH, Ioannidis JP, Carrington M, Murphy PM, Havlir DV, Richman DD.
Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy.
AIDS. 14: 821-6, 2000.
[Journal]
202)  Vorechovsky I, Cullen M, Carrington M, Hammarstrom L, Webster AD.
Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency: identification and characterization of haplotypes shared by affected members of 101 multiple-case families.
J. Immunol. 164: 4408-16, 2000.
[Journal]
203)  An P, Martin MP, Nelson GW, Carrington M, Smith MW, Gong K, Vlahov D, O'Brien SJ, Winkler CA.
Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans.
AIDS. 14: 2117-22, 2000.
[Journal]
204)  El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Rabkin CS.
Interleukin-1 polymorphisms associated with increased risk of gastric cancer.
Nature. 404: 398-402, 2000.
[Journal]
205)  Bream JH, Carrington M, O'Toole S, Dean M, Gerrard B, Shin HD, Kosack D, Modi W, Young HA, Smith MW.
Polymorphisms of the human IFNG gene noncoding regions.
Immunogenetics. 51: 50-8, 2000.
[Journal]
206)  Huttley GA, Smith MW, Carrington M, O'Brien SJ.
A scan for linkage disequilibrium across the human genome.
Genetics. 152: 1711-22, 1999.
[Journal]
207)  Bream JH, Young HA, Rice N, Martin MP, Smith MW, Carrington M, O'Brien SJ.
CCR5 promoter alleles and specific DNA binding factors.
Science. 284: 223, 1999.
[Journal]
208)  Thio CL, Carrington M, Marti D, O'Brien SJ, Vlahov D, Nelson KE, Astemborski J, Thomas DL.
Class II HLA alleles and hepatitis B virus persistence in African Americans.
J. Infect. Dis. 179: 1004-6, 1999.
[Journal]
209)  Lockett SF, Alonso A, Wyld R, Martin MP, Robertson JR, Gore SM, Leen CL, Brettle RP, Yirrell DL, Carrington M, Brown AJ.
Effect of chemokine receptor mutations on heterosexual human immunodeficiency virus transmission.
J. Infect. Dis. 180: 614-21, 1999.
[Journal]
210)  Carrington M, Dean M, Martin MP, O'Brien SJ.
Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences.
Hum. Mol. Genet. 8: 1939-45, 1999.
[Journal]
211)  Carrington M, Nelson GW, Martin MP, Kissner T, Vlahov D, Goedert JJ, Kaslow R, Buchbinder S, Hoots K, O'Brien SJ.
HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage.
Science. 283: 1748-52, 1999.
[Journal]
212)  Howard OM, Shirakawa AK, Turpin JA, Maynard A, Tobin GJ, Carrington M, Oppenheim JJ, Dean M.
Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function.
J. Biol. Chem. 274: 16228-34, 1999.
[Journal]
213)  Hendel H, Caillat-Zucman S, Lebuanec H, Carrington M, O'Brien S, Andrieu JM, Schächter F, Zagury D, Rappaport J, Winkler C, Nelson GW, Zagury JF.
New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS.
J. Immunol. 162: 6942-6, 1999.
[Journal]
214)  Nguyen GT, Carrington M, Beeler JA, Dean M, Aledort LM, Blatt PM, Cohen AR, DiMichele D, Eyster ME, Kessler CM, Konkle B, Leissinger C, Luban N, O'Brien SJ, Goedert JJ, O'Brien TR.
Phenotypic expressions of CCR5-delta32/delta32 homozygosity.
J. Acquir. Immune Defic. Syndr. 22: 75-82, 1999.
[Journal]
215)  Carrington M.
Recombination within the human MHC.
Immunol. Rev. 167: 245-56, 1999.
[Journal]
216)  Dean M, Jacobson LP, McFarlane G, Margolick JB, Jenkins FJ, Howard OM, Dong HF, Goedert JJ, Buchbinder S, Gomperts E, Vlahov D, Oppenheim JJ, O'Brien SJ, Carrington M.
Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-delta32 mutation.
Cancer Res. 59: 3561-4, 1999.
[Journal]
217)  McKenzie LM, Pecon-Slattery J, Carrington M, O'Brien SJ.
Taxonomic hierarchy of HLA class I allele sequences.
Genes Immun. 1: 120-9, 1999.
[Journal]
218)  Saah AJ, Hoover DR, Weng S, Carrington M, Mellors J, Rinaldo CR, Mann D, Apple R, Phair JP, Detels R, O'Brien S, Enger C, Johnson P, Kaslow RA.
Association of HLA profiles with early plasma viral load, CD4+ cell count and rate of progression to AIDS following acute HIV-1 infection. Multicenter AIDS Cohort Study.
AIDS. 12: 2107-13, 1998.
[Journal]
219)  O'Brien TR, Padian NS, Hodge T, Goedert JJ, O'Brien SJ, Carrington M.
CCR-5 genotype and sexual transmission of HIV-1.
AIDS. 12: 444-5, 1998.
[Journal]
220)  Martin MP, Harding A, Chadwick R, Kronick M, Cullen M, Lin L, Mignot E, Carrington M.
Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines.
Immunogenetics. 47: 131-8, 1998.
[Journal]
221)  Martin M, Harding A, Chadwwick R, Kronick M, Cullen M, Lin L, Mignot E, Carrington M.
Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines.
Immunogenetics. 47: 503, 1998.
[Journal]
222)  Martin MP, Carrington M, Dean M, O'Brien SJ, Sheppard HW, Wegner SA, Michael NL.
CXCR4 polymorphisms and HIV-1 pathogenesis.
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 19: 430, 1998.
[Journal]
223)  Stephens JC, Reich DE, Goldstein DB, Shin HD, Smith MW, Carrington M, Winkler C, Huttley GA, Allikmets R, Schriml L, Gerrard B, Malasky M, Ramos MD, Morlot S, Tzetis M, Oddoux C, di Giovine FS, Nasioulas G, Chandler D, Aseev M, Hanson M, Kalaydjieva L, Glavac D, Gasparini P, Kanavakis E, Claustres M, Kambouris M, Ostrer H, Duff G, Baranov V, Sibul H, Metspalu A, Goldman D, Martin N, Duffy D, Schmidtke J, Estivill X, O'Brien SJ, Dean M.
Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes.
Am. J. Hum. Genet. 62: 1507-15, 1998.
[Journal]
224)  Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, Lee B, Doms RW, Margolick J, Buchbinder S, Goedert JJ, O'Brien TR, Hilgartner MW, Vlahov D, O'Brien SJ, Carrington M.
Genetic acceleration of AIDS progression by a promoter variant of CCR5.
Science. 282: 1907-11, 1998.
[Journal]
225)  Winkler C, Modi W, Smith MW, Nelson GW, Wu X, Carrington M, Dean M, Honjo T, Tashiro K, Yabe D, Buchbinder S, Vittinghoff E, Goedert JJ, O'Brien TR, Jacobson LP, Detels R, Donfield S, Willoughby A, Gomperts E, Vlahov D, Phair J, O'Brien SJ.
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC).
Science. 279: 389-93, 1998.
[Journal]
226)  Hildesheim A, Schiffman M, Scott DR, Marti D, Kissner T, Sherman ME, Glass AG, Manos MM, Lorincz AT, Kurman RJ, Buckland J, Rush BB, Carrington M.
Human leukocyte antigen class I/II alleles and development of human papillomavirus-related cervical neoplasia: results from a case-control study conducted in the United States.
Cancer Epidemiol. Biomarkers Prev. 7: 1035-41, 1998.
[Journal]
227)  Hildesheim A, Schiffman M, Brinton LA, Fraumeni JF, Herrero R, Bratti MC, Schwartz P, Mortel R, Barnes W, Greenberg M, McGowan L, Scott DR, Martin M, Herrera JE, Carrington M.
p53 polymorphism and risk of cervical cancer.
Nature. 396: 531-2, 1998.
[Journal]
228)  Smith MW, Carrington M, Winkler C, Lomb D, Dean M, Huttley G, O'Brien SJ.
CCR2 chemokine receptor and AIDS progression.
Nat. Med. 3: 1052-3, 1997.
[Journal]
229)  Smith MW, Dean M, Carrington M, Huttley GA, O'Brien SJ.
CCR5-delta 32 gene deletion in HIV-1 infected patients.
Lancet. 350: 741; author reply 742, 1997.
[Journal]
230)  Cullen M, Noble J, Erlich H, Thorpe K, Beck S, Klitz W, Trowsdale J, Carrington M.
Characterization of recombination in the HLA class II region.
Am. J. Hum. Genet. 60: 397-407, 1997.
[Journal]
231)  Barcellos LF, Thomson G, Carrington M, Schafer J, Begovich AB, Lin P, Xu XH, Min BQ, Marti D, Klitz W.
Chromosome 19 single-locus and multilocus haplotype associations with multiple sclerosis. Evidence of a new susceptibility locus in Caucasian and Chinese patients.
JAMA. 278: 1256-61, 1997.
[Journal]
232)  Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, Lomb DA, Goedert JJ, O'Brien TR, Jacobson LP, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner MW, O'Brien SJ.
Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study.
Science. 277: 959-65, 1997.
[Journal]
233)  Lin L, Jin L, Kimura A, Carrington M, Mignot E.
DQ microsatellite association studies in three ethnic groups.
Tissue Antigens. 50: 507-20, 1997.
[Journal]
234)  Malfroy L, Roth MP, Carrington M, Borot N, Volz A, Ziegler A, Coppin H.
Heterogeneity in rates of recombination in the 6-Mb region telomeric to the human major histocompatibility complex.
Genomics. 43: 226-31, 1997.
[Journal]
235)  O'Brien TR, Winkler C, Dean M, Nelson JA, Carrington M, Michael NL, White GC.
HIV-1 infection in a man homozygous for CCR5 delta 32.
Lancet. 349: 1219, 1997.
[Journal]
236)  Carrington M, Stephens JC, Ma WY, Martin M, Harding A, Noble J, Erlich H, Mann D, Arango C, Jaramillo R, Concha M, Maloney E, Blattner W.
Identification of a novel TAP2 allele in a Colombian black population: gene conversion, ancestral intermediate or convergent change?.
Mol. Biol. Evol. 14: 892-4, 1997.
[Journal]
237)  Carrington M, Kissner T, Gerrard B, Ivanov S, O'Brien SJ, Dean M.
Novel alleles of the chemokine-receptor gene CCR5.
Am. J. Hum. Genet. 61: 1261-7, 1997.
[Journal]
238)  Kurokohchi K, Carrington M, Mann DL, Simonis TB, Alexander-Miller MA, Feinstone SM, Akatsuka T, Berzofsky JA.
Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma.
Hepatology. 23: 1181-8, 1996.
[Journal]
239)  Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, Goedert JJ, Buchbinder SP, Vittinghoff E, Gomperts E, Donfield S, Vlahov D, Kaslow R, Saah A, Rinaldo C, Detels R, O'Brien SJ.
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study.
Science. 273: 1856-62, 1996.
[Journal]
240)  Kaslow RA, Carrington M, Apple R, Park L, Muñoz A, Saah AJ, Goedert JJ, Winkler C, O'Brien SJ, Rinaldo C, Detels R, Blattner W, Phair J, Erlich H, Mann DL.
Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection.
Nat. Med. 2: 405-11, 1996.
[Journal]
241)  Tsukui T, Hildesheim A, Schiffman MH, Lucci J, Contois D, Lawler P, Rush BB, Lorincz AT, Corrigan A, Burk RD, Qu W, Marshall MA, Mann D, Carrington M, Clerici M, Shearer GM, Carbone DP, Scott DR, Houghten RA, Berzofsky JA.
Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology.
Cancer Res. 56: 3967-74, 1996.
[Journal]
242)  Thomsen M, Cullen M, Carrington M, Foissac A, Abbal M, de Préval C, Crouau-Roy B, Cambon-Thomsen A.
Localization of the recombination points in a family with two DR/DP recombinations.
Tissue Antigens. 47: 492-7, 1996.
[Journal]
243)  Hughes AL, Yeager M, Carrington M.
Peptide binding function and the paradox of HLA disease associations.
Immunol. Cell Biol. 74: 444-8, 1996.
[Journal]
244)  Detels R, Mann D, Carrington M, Hennessey K, Wu Z, Hirji KF, Wiley D, Visscher BR, Giorgi JV.
Persistently seronegative men from whom HIV-1 has been isolated are genetically and immunologically distinct.
Immunol. Lett. 51: 29-33, 1996.
[Journal]
245)  Detels R, Mann D, Carrington M, Hennessey K, Wu Z, Hirji KF, Wiley D, Visscher BR, Giorgi JV.
Resistance to HIV infection may be genetically mediated.
AIDS. 10: 102-4, 1996.
[Journal]
246)  Carrington M, Wade J.
Selection of transplant donors based on MHC microsatellite data.
Hum. Immunol. 50: 151-4, 1996.
[Journal]
247)  Carrington M, Wade J.
Selection of transplant donors based on MHC microsatellite data.
Hum. Immunol. 51: 106-9, 1996.
[Journal]
248)  Kim TG, Carrington M, Choi HB, Kim HY, Han H.
Three HLA-DMB variants in Korean patients with autoimmune diseases.
Hum. Immunol. 46: 58-60, 1996.
[Journal]
249)  Kroner BL, Goedert JJ, Blattner WA, Wilson SE, Carrington MN, Mann DL.
Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia Cohort and Hemophilia Growth and Development Studies.
AIDS. 9: 275-80, 1995.
[Journal]
250)  Klitz W, Stephens JC, Grote M, Carrington M.
Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region.
Am. J. Hum. Genet. 57: 1436-44, 1995.
[Journal]
251)  Cullen M, Erlich H, Klitz W, Carrington M.
Molecular mapping of a recombination hotspot located in the second intron of the human TAP2 locus.
Am. J. Hum. Genet. 56: 1350-8, 1995.
[Journal]
252)  Martin M, Mann D, Carrington M.
Recombination rates across the HLA complex: use of microsatellites as a rapid screen for recombinant chromosomes.
Hum. Mol. Genet. 4: 423-8, 1995.
[Journal]
253)  Barron KS, Reveille JD, Carrington M, Mann DL, Robinson MA.
Susceptibility to Reiter's syndrome is associated with alleles of TAP genes.
Arthritis Rheum. 38: 684-9, 1995.
[Journal]
254)  Carrington M, Dean M.
A polymorphic dinucleotide repeat in the third intron of TAP1.
Hum. Mol. Genet. 3: 218, 1994.
[Journal]
255)  Carrington M, Krueger LJ, Holsclaw DS, Iannuzzi MC, Dean M, Mann D.
Cystic fibrosis-related diabetes is associated with HLA DQB1 alleles encoding Asp-57- molecules.
J. Clin. Immunol. 14: 353-8, 1994.
[Journal]
256)  Carrington M, Stephens JC, Klitz W, Begovich AB, Erlich HA, Mann D.
Major histocompatibility complex class II haplotypes and linkage disequilibrium values observed in the CEPH families.
Hum. Immunol. 41: 234-40, 1994.
[Journal]
257)  Carrington M, Harding A.
Sequence analysis of two novel HLA-DMA alleles.
Immunogenetics. 40: 165, 1994.
[Journal]
258)  Zimmerman PA, Carrington MN, Nutman TB.
Exploiting structural differences among heteroduplex molecules to simplify genotyping the DQA1 and DQB1 alleles in human lymphocyte typing.
Nucleic Acids Res. 21: 4541-7, 1993.
[Journal]
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