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Our Science – Young Website

Howard A. Young, Ph.D.

Selected Publications

1)  Barrios B, Baez NS, Reynolds D, Iribarren P, Cejas H, Young HA, Rodriguez-Galan MC.
Abrogation of TNFa Production during Cancer Immunotherapy Is Crucial for Suppressing Side Effects Due to the Systemic Expression of IL-12.
PLoS ONE. 9: e90116, 2014.
2)  Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HA.
IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.
J. Autoimmun. 2014.
3)  Savan R, McFarland AP, Reynolds DA, Feigenbaum L, Ramakrishnan K, Karwan M, Shirota H, Klinman DM, Dunleavy K, Pittaluga S, Anderson SK, Donnelly RP, Wilson WH, Young HA.
A novel role for IL-22R1 as a driver of inflammation.
Blood. 117: 575-84, 2011.
4)  Kulkarni S, Savan R, Qi Y, Gao X, Yuki Y, Bass SE, Martin MP, Hunt P, Deeks SG, Telenti A, Pereyra F, Goldstein D, Wolinsky S, Walker B, Young HA, Carrington M.
Differential microRNA regulation of HLA-C expression and its association with HIV control.
Nature. 472: 495-8, 2011.
5)  McFarland AP, Savan R, Wagage S, Addison A, Ramakrishnan K, Karwan M, Duong T, Young HA.
Localized delivery of interferon-beta by Lactobacillus exacerbates experimental colitis.
PLoS ONE. 6: e16967, 2011.
6)  Hodge DL, Reynolds D, Cerbán FM, Correa SG, Baez NS, Young HA, Rodriguez-Galan MC.
MCP-1/CCR2 interactions direct migration of peripheral B and T lymphocytes to the thymus during acute infectious/inflammatory processes.
Eur. J. Immunol. 42: 2644-54, 2012.
7)  Xiao Z, Jiang Q, Willette-Brown J, Xi S, Zhu F, Burkett S, Back T, Song NY, Datla M, Sun Z, Goldszmid R, Lin F, Cohoon T, Pike K, Wu X, Schrump DS, Wong KK, Young HA, Trinchieri G, Wiltrout RH, Hu Y.
The Pivotal Role of IKKa in the Development of Spontaneous Lung Squamous Cell Carcinomas.
Cancer Cell. 23: 527-40, 2013.
8)  Kaczmarczyk SJ, Sitaraman K, Young HA, Hughes SH, Chatterjee DK.
Protein delivery using engineered virus-like particles.
Proc. Natl. Acad. Sci. U.S.A. 108: 16998-7003, 2011.
9)  Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL.
Interferon-ß Therapy Prolongs Survival in Rhesus Macaque Models of Ebola and Marburg Hemorrhagic Fever.
J. Infect. Dis. [Epub ahead of print], 2013.
10)  Kawayama T, Okamoto M, Imaoka H, Kato S, Young HA, Hoshino T.
Interleukin-18 in pulmonary inflammatory diseases.
J. Interferon Cytokine Res. 32: 443-9, 2012.
Click Here to View Expanded Bibliography.

This page was last updated on 4/3/2014.