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Our Science – Keller Website

Jonathan R. Keller, Ph.D.

Selected Publications

1)  Keller JR, Mantel C, Sing GK, Ellingsworth LR, Ruscetti SK, Ruscetti FW.
Transforming growth factor beta 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines.
J. Exp. Med. 168: 737-50, 1988.
2)  Ortiz M, Wine JW, Lohrey N, Ruscetti FW, Spence SE, Keller JR.
Functional characterization of a novel hematopoietic stem cell and its place in the c-Kit maturation pathway in bone marrow cell development.
Immunity. 10: 173-82, 1999.
3)  Smith JS, Keller JR, Lohrey NC, McCauslin CS, Ortiz M, Cowan K, Spence SE.
Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens.
Proc. Natl. Acad. Sci. U.S.A. 96: 8855-60, 1999.
4)  Heath V, Suh HC, Holman M, Renn K, Gooya JM, Parkin S, Klarmann KD, Ortiz M, Johnson P, Keller J.
C/EBP{alpha} Deficiency Results in Hyperproliferation of Hematopoietic Progenitor Cells and Disrupts Macrophage Development In Vitro and In Vivo.
Blood. 104: 1639-47, 2004.
5)  Li H, Ji M, Klarmann KD, Keller JR.
Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid development.
Blood. 116: 1060-9, 2010.
6)  Huggins CJ, Malik R, Lee S, Salotti J, Thomas S, Martin N, Quiñones OA, Alvord WG, Olanich ME, Keller JR, Johnson PF.
C/EBP? Suppresses Senescence and Inflammatory Gene Expression by Heterodimerizing with C/EBPß.
Mol. Cell. Biol. 33: 3242-58, 2013.
7)  Sun L, Mathews LA, Cabarcas SM, Zhang X, Yang A, Zhang Y, Young MR, Klarmann KD, Keller JR, Farrar WL.
Epigenetic Regulation of SOX9 by the NF-?B Signaling Pathway in Pancreatic Cancer Stem Cells.
Stem Cells. 31: 1454-66, 2013.
8)  Balamurugan K, Sharan S, Klarmann KD, Zhang Y, Coppola V, Summers GH, Roger T, Morrison DK, Keller JR, Sterneck E.
FBXW7alpha attenuates inflammatory signalling by downregulating C/EBPdelta and its target gene Tlr4.
Nat Commun. 4: 1662, 2013.
9)  Singh SK, Williams CA, Klarmann K, Burkett SS, Keller JR, Oberdoerffer P.
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.
J. Exp. Med. 210: 987-1001, 2013.
10)  Aiello FB, Graciotti L, Procopio AD, Keller JR, Durum SK.
Stemness of T cells and the hematopoietic stem cells: fate, memory, niche, cytokines.
Cytokine Growth Factor Rev. 24: 485-501, 2013.
Click Here to View Expanded Bibliography.

This page was last updated on 6/30/2014.