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Our Science – Hatfield Website

Dolph L. Hatfield, Ph.D.

Selected Publications

1)  Xu X, Carlson BA, Mix H, Zhang Y, Saira K, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL.
Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes.
PLoS Biol. 5: e4, 2007.
2)  Xu XM, Turanov AA, Carlson BA, Yoo MH, Everley RA, Nandakumar R, Sorokina I, Gygi SP, Gladyshev VN, Hatfield DL.
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery.
Proc. Natl. Acad. Sci. U.S.A. 107: 21430-4, 2010.
3)  Yoo M, Carlson B, Tsuji P, Tobe R, Naranjo-Suarez S, Lee B, Davis C, Gladyshev V, Hatfield D.
Hatfield D, Berry M, Gladyshev V, eds.
Selenoproteins harboring a split personality in both preventing and promoting cancer. In: Selenium: Its molecular biology and role in human health. Volume 3.
New York: Springer Science+Business Media, LLC; 2012. p. 325-334 [Book Chapter]
4)  Carlson BA, Yoo M, Tobe R, Mueller C, Naranjo-Suarez S, Hoffmann VJ, Gladyshev VN, Hatfield DL.
Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis.
Carcinogenesis. 33: 1806-13, 2012.
5)  Yoo MH, Carlson BA, Gladyshev VN, Hatfield DL.
Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-a-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus.
PLoS ONE. 8: e71427, 2013.
6)  Seeher S, Carlson BA, Miniard AC, Wirth EK, Mahdi Y, Hatfield DL, Driscoll DM, Schweizer U.
Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to coordination defects in mice.
Biochem. J. 2014.
7)  Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, Tavares de Almeida I, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE.
Inhibition of Cellular Methyltransferases Promotes Endothelial Cell Activation by Suppressing Glutathione Peroxidase-1 Expression.
J. Biol. Chem. [Epub ahead of print], 2014.
8)  Seeher S, Atassi T, Mahdi Y, Carlson BA, Braun D, Wirth EK, Klein MO, Reix N, Miniard AC, Schomburg L, Hatfield DL, Driscoll DM, Schweizer U.
Secisbp2 Is Essential for Embryonic Development and Enhances Selenoprotein Expression.
Antioxid. Redox Signal. [Epub ahead of print], 2014.
9)  Hatfield DL, Tsuji PA, Carlson BA, Gladyshev VN.
Selenium and selenocysteine: roles in cancer, health, and development.
Trends Biochem. Sci. 39: 112-20, 2014.
10)  Turanov AA, Shchedrina VA, Everley RA, Lobanov AV, Yim SH, Marino SM, Gygi SP, Hatfield DL, Gladyshev VN.
Selenoprotein S is Involved in Maintenance and Transport of Multiprotein Complexes.
Biochem. J. 2014.
Click Here to View Expanded Bibliography.

This page was last updated on 6/27/2014.