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Ira O. Daar, Ph.D.

Selected Publications

1)  Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO.
The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.
Genes Dev. 27: 491-503, 2013.
2)  Lee H, Nishanian TG, Mood K, Bong Y, Daar IO.
EphrinB1 controls cell-cell junctions through the Par polarity complex.
Nat. Cell Biol. 10: 979-86, 2008.
Full Text Article. [Journal]
3)  Bong Y, Lee H, Carim-Todd L, Mood K, Nishanian TG, Tessarollo L, Daar IO.
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3.
Proc Natl Acad Sci U S A. 104: 17305-17310, 2007.
Full Text Article. [Journal]
4)  Lee H, Bong Y, Moore KB, Soria K, Moody SA, Daar IO.
Dishevelled mediates ephrinB1 signalling in the eye field through the planar cell polarity pathway.
Nat Cell Biol. 8: 55-63, 2006.
Full Text Article. [Journal]
5)  Jones TL, Chong LD, Kim J, Xu RH, Kung HF, Daar IO.
Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand.
Proc. Natl. Acad. Sci. U.S.A. 95: 576-81, 1998.
6)  Cho HJ, Hwang Y, Mood K, Ji YJ, Lim J, Morrison DK, Daar IO.
EphrinB1 Interacts with CNK1 and Promotes Cell Migration through JNK Activation.
J. Biol. Chem. 289: 18556-18568, 2014.
7)  Ji YJ, Hwang YS, Mood K, Cho HJ, Lee HS, Winterbottom E, Cousin H, Daar IO.
EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1.
Nat Commun. 5: 3516, 2014.
8)  Singh A, Winterbottom EF, Ji YJ, Hwang Y, Daar IO.
Abl Interactor 1 (Abi1) and its Interaction with Wiskott Aldrich Syndrome Protein (Wasp) are Critical for Proper Eye Formation in Xenopus Embryos.
J. Biol. Chem. 288: 14135-46, 2013.
Full Text Article. [Journal]
9)  Klein SL, Neilson KM, Orban J, Yaklichkin S, Hoffbauer J, Mood K, Daar IO, Moody SA.
Conserved Structural Domains in FoxD4L1, a Neural Forkhead Box Transcription Factor, Are Required to Repress or Activate Target Genes.
PLoS ONE. 8: e61845, 2013.
10)  Singh A, Winterbottom E, Daar IO.
Eph/ephrin signaling in cell-cell and cell-substrate adhesion.
Front. Biosci. 17: 473-97, 2012.
11)  Daar IO.
Non-SH2/PDZ reverse signaling by ephrins.
Semin Cell Dev Biol. 23(1): 65-74, 2012.
12)  Bulut G, Hong S, Chen K, Beauchamp EM, Rahim S, Kosturko GW, Glasgow E, Dakshanamurthy S, Lee H, Daar I, Toretsky JA, Khanna C, Uren A.
Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.
Oncogene. 31(3): 269-81, 2012.
13)  Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA.
Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate.
Dev Biol. 365(2): 363-75, 2012.
14)  Lee HS, Sokol SY, Moody SA, Daar IO.
Using 32-Cell Stage Xenopus Embryos to Probe PCP Signaling.
Methods Mol. Biol. 839: 91-104, 2012.
15)  Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL.
Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.
Dev. Cell. 19: 413-25, 2010.
16)  Lee H, Daar IO.
EphrinB Reverse Signaling in Cell-Cell Adhesion: Is it Just Par for the Course?.
Cell Adhesion & Migration. 3: 250-255, 2009.
Full Text Article. [Journal]
17)  Lee H, Mood K, Battu G, Ji YJ, Singh A, Daar IO.
FGF receptor-induced phosphorylation of ephrinB1 modulates its interaction with dishevelled.
Mol Biol Cell. 20: 124-33, 2009.
Full Text Article. [Journal]
18)  Daar I.
Moody S, eds.
The roles of Ephrin-Eph signaling in morphogenesis. In: Principles of Developmental Genetics.
San Diego: Elsevier/Academic Press; 2007. p. 467-498 [Book Chapter]
19)  Mood K, Saucier C, Bong Y, Lee H, Park M, Daar IO.
Gab1 Is required for cell-cycle transition, cell proliferation, and transformation induced by an oncogenic Met receptor.
Mol. Biol. Cell. 17: 3717-3728, 2006.
Full Text Article. [Journal]
20)  Ritt DA, Daar IO, Morrison DK.
KSR regulation of the Raf-MEK-ERK cascade.
Meth. Enzymol. 407: 224-37, 2006.
21)  Mood K, Saucier C, Ishimura A, Bong YS, Lee HS, Park M, Daar IO.
Oncogenic Met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and Shc binding or Mos synthesis, but requires PI-3K and Raf Signaling.
J. Cell Phys. 207: 271-285, 2006.
22)  Ishimura A, Lee H, Bong Y, Saucier C, Mood K, Park EK, Daar IO.
Oncogenic Met receptor induces ectopic structures in Xenopus embryos.
Oncogene. 25: 4286-99, 2006.
23)  Chen ZQ, Dong J, Ishimura A, Daar I, Hinnebusch AG, Dean M.
The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors.
J Biol Chem. 281: 7452-7, 2006.
Full Text Article. [Journal]
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This page was last updated on 7/3/2014.