Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health
CCR - For Our Staff| Home |

Our Science – Acharya Website

Jairaj K. Acharya, MBBS, Ph.D.

Selected Publications

1)  Rao RP, Scheffer L, Srideshikan SM, Parthibane V, Kosakowska-Cholody T, Masood MA, Nagashima K, Gudla P, Lockett S, Acharya U, Acharya JK.
Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells.
PLoS ONE. 9: e92142, 2014.
2)  Masood MA, Rao RP, Acharya JK, Blonder J, Veenstra TD.
Quantitation of multiple sphingolipid classes using normal and reversed-phase LC-ESI-MS/MS: comparative profiling of two cell lines.
Lipids. 47: 209-26, 2012.
3)  Yuan C, Rao RP, Jesmin N, Bamba T, Nagashima K, Pascual A, Preat T, Fukusaki E, Acharya U, Acharya JK.
CDase is a pan-ceramidase in Drosophila.
Mol. Biol. Cell. 22: 33-43, 2011.
4)  Scheffer L, Raghavendra PR, Jing-Jing M, Acharya JK.
Ceramide Transfer Protein and Cancer.
Anticancer Agents Med Chem. 11: 904-10, 2011.
5)  Yonamine I, Bamba T, Nirala N, Jasmin N, Kosakowska-Cholody T, Nagashima K, Eiichiro F, Acharya JK, Acharya U.
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors.
J Cell Biol. 192: 557-567, 2011.
Full Text Article. [Journal]
6)  Masood MA, Yuan C, Acharya JK, Veenstra TD, Blonder J.
Quantitation of ceramide phosphorylethanolamines containing saturated and unsaturated sphingoid base cores.
Anal. Biochem. 400: 259-69, 2010.
7)  Dasgupta U, Bamba T, Chiantia S, Karim P, Abou Tayoun AN, Yonamine I, Rawat SS, Rao RP, Nagashima K, Fukusaki E, Puri V, Dolph PJ, Schwille P, Acharya JK, Acharya U.
Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction.
Proc. Natl. Acad. Sci. U.S.A. 106: 20063-8, 2009.
8)  Wang X, Pralhada Rao R, Kosakowska-Cholody T, Athar Masood M, Southon E, Zhang H, Berthet C, Nagashima K, Veenstra TK, Tessarollo L, Acharya U, Acharya JK.
Mitochondrial Degeneration and Not Apoptosis is the Primary cause of Embryonic Lethality in Ceramide Transfer Protein Mutant Mice.
J Cell Biol. 184: 143-158, 2009.
Full Text Article. [Journal]
9)  Acharya JK, Dasgupta U, Rawat SS, Yuan C, Sanxaridis PD, Yonamine I, Karim P, Nagashima K, Brodsky MH, Tsunoda S, Acharya U.
Cell non-autonomous function of ceramidase in photoreceptor homeostasis.
Neuron. 57: 69-79, 2008.
Full Text Article. [Journal]
10)  Pralhada Rao R, Yuan C, Allegood JC, Rawat SS, Edwards M, Wang X, Merrill Jr AH, Acharya U, Acharya JK.
Ceramide transfer protein function is essential for normal oxidative stress response and lifespan.
Proc Natl Acad Sci USA. 27: 11364-11369, 2007.
11)  Acharya U, Edwards MB, Jorquera RA, Silva H, Nagashima K, Labarca P, Acharya JK.
Drosophila melanogaster scramblases modulate synaptic transmission.
J Cell Biol. 173: 69-82, 2006.
12)  Acharya U, Mowen MB, Nagashima K, Acharya JK.
Ceramidase expression facilitates membrane turnover and endocytosis of rhodopsin in photoreceptors.
Proc Natl Acad Sci U S A. 101(7): 1922-1926, 2004.
13)  Acharya U, Patel S, Koundakjian E, Nagashima K, Han X, Acharya JK.
Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration.
Science. 299: 1740-3, 2003.
14)  Acharya U, Mallabiabarrena A, Acharya JK, Malhotra V.
Signaling via mitogen-activated protein kinase kinase (MEK1) is required for Golgi fragmentation during mitosis.
Cell. 92: 183-92, 1998.
15)  Acharya JK, Labarca P, Delgado R, Jalink K, Zuker CS.
Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants.
Neuron. 20: 1219-29, 1998.
16)  Acharya JK, Jalink K, Hardy RW, Hartenstein V, Zuker CS.
InsP3 receptor is essential for growth and differentiation but not for vision in Drosophila.
Neuron. 18: 881-7, 1997.
17)  Gossen M, Pak DT, Hansen SK, Acharya JK, Botchan MR.
A Drosophila homolog of the yeast origin recognition complex.
Science. 270: 1674-7, 1995.
18)  Acharya JK, Rao NA.
A novel intermediate in the interaction of thiosemicarbazide with sheep liver serine hydroxymethyltransferase.
J Biol Chem. 267: 19066-71, 1992.
Click Here to View Collapsed Bibliography.

This page was last updated on 4/21/2014.