Our Science – Sharan Website
Shyam K. Sharan, Ph.D.
Selected Publications |
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| 1)
Chang S, Sharan SK. The role of epigenetic transcriptional regulation in BRCA1-mediated tumor suppression. Transcription. Jan-Feb;4(1): 24-28, 2013. Full Text Article. [Journal] |
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| 2)
Chang S, Sharan SK. BRCA1 and MicroRNAs: Emerging networks and potential therapeutic targets. Mol. Cells. 34: 425-32, 2012. [Journal] |
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| 3)
Chang S, Sharan SK. Epigenetic control of an oncogenic microRNA, miR-155, by BRCA1. Oncotarget. 3: 5-6, 2012. [Journal] |
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| 4)
Biswas K, Das R, Eggington JM, Qiao H, North SL, Stauffer S, Burkett SS, Martin BK, Southon E, Sizemore SC, Pruss D, Bowles KR, Roa BB, Hunter N, Tessarollo L, Wenstrup RJ, Byrd RA, Sharan SK. Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay. Hum. Mol. Genet. 21: 3993-4006, 2012. [Journal] |
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| 5)
Chang S, Wang RH, Akagi K, Kim KA, Martin BK, Cavallone L, Haines DC, Basik M, Mai P, Poggi E, Isaacs C, Looi LM, Mun KS, Greene MH, Byers SW, Teo SH, Deng CX, Sharan SK. Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155. Nat. Med. 17: 1275-82, 2011. [Journal] |
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| 6)
Biswas K, Das R, Alter BP, Kuznetsov SG, Stauffer S, North SL, Burkett S, Brody LC, Meyer S, Byrd RA, Sharan SK. A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay. Blood. 118: 2430-42, 2011. [Journal] |
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| 7)
Chang S, Biswas K, Martin BK, Stauffer S, Sharan SK. Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations. J. Clin. Invest. 119: 3160-71, 2009. [Journal] |
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| 8)
Sharan SK, Thomason LC, Kuznetsov SG, Court DL. Recombineering: a homologous recombination-based method of genetic engineering. Nat Protoc. 4: 206-23, 2009. [Journal] |
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| 9)
Kuznetsov SG, Liu P, Sharan SK. Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2. Nat. Med. 14: 875-81, 2008. [Journal] |
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| 10)
Philip S, Swaminathan S, Kuznetsov SG, Kanugula S, Biswas K, Chang S, Loktionova NA, Haines DC, Kaldis P, Pegg AE, Sharan SK. Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications. Cancer Res. 68: 9973-81, 2008. [Journal] |
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| Click Here to View Expanded Bibliography. |
This page was last updated on 4/30/2013.
