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Our Science – KewalRamani Website

Vineet N. KewalRamani, Ph.D.

Selected Publications

1)  Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Oztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, Kewalramani VN, Fassati A, Engelman A, Cherepanov P.
Structural basis for nuclear import of splicing factors by human Transportin 3.
Proc. Natl. Acad. Sci. U.S.A. 111: 2728-33, 2014.
2)  Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, Kewalramani VN, Hughes SH, Engelman A.
Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration.
J. Virol. 87: 648-58, 2013.
3)  Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, Kewalramani VN, Chin JW, Towers GJ, James LC.
CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication.
PLoS Pathog. 8: e1002896, 2012.
4)  Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, Kewalramani VN.
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.
J. Virol. 86: 4708-14, 2012.
5)  Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, Kewalramani VN.
HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6.
J Virol. 3851-60, 2012.
6)  Lee K, Ambrose Z, Martin T, Oztop I, Mulky A, Julias J, Vandegraaff N, Baumann J, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman D, Coffin J, Hughes S, Unutmaz D, Engelman A, KewalRamani V.
Flexible use of nuclear import pathways by HIV-1.
Cell Host Microbe. 7: 221-233, 2010.
7)  Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD.
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
J. Virol. 86: 3152-66, 2012.
8)  Boltz VF, Ambrose Z, Kearney MF, Shao W, Kewalramani VN, Maldarelli F, Mellors JW, Coffin JM.
Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase.
J. Virol. 86: 12525-30, 2012.
9)  Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, Kewalramani VN, Mellors JW, Coffin JM, Ambrose Z.
Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy.
J. Virol. 85: 1067-76, 2011.
10)  Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, Kewalramani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ.
HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency.
PLoS Pathog. 7: e1002439, 2011.
Click Here to View Expanded Bibliography.

This page was last updated on 2/21/2014.