Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health www.cancer.gov
CCR - For Our Staff| Home |

Our Science – Pavlakis Website

George N. Pavlakis, M.D., Ph.D.

Selected Publications

1)  Felber BK, Hadzopoulou-Cladaras M, Cladaras C, Copeland T, Pavlakis GN.
rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.
Proc. Natl. Acad. Sci. U.S.A. 86: 1495-9, 1989.
[Journal]
2)  Schwartz S, Campbell M, Nasioulas G, Harrison J, Felber BK, Pavlakis GN.
Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression.
J. Virol. 66: 7176-82, 1992.
[Journal]
3)  Templeton NS, Lasic DD, Frederik PM, Strey HH, Roberts DD, Pavlakis GN.
Improved DNA: liposome complexes for increased systemic delivery and gene expression.
Nat. Biotechnol. 15: 647-52, 1997.
[Journal]
4)  Bergamaschi C, Bear J, Rosati M, Kelly Beach R, Alicea C, Sowder R, Chertova E, Rosenberg SA, Felber BK, Pavlakis GN.
Circulating interleukin-15 (IL-15) exists as heterodimeric complex with soluble IL-15 receptor alpha (IL-15Rα) in human serum.
Blood. 120: e1-8, 2012.
[Journal]
5)  Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, Alicea C, von Gegerfelt A, Huang W, Guan Y, Keele BF, Bess JW, Piatak M, Lifson JD, Williams WT, Shen X, Tomaras GD, Amara RR, Robinson HL, Johnson W, Broderick KE, Sardesai NY, Venzon DJ, Hirsch VM, Felber BK, Pavlakis GN.
DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
Proc. Natl. Acad. Sci. U.S.A. 110: 2975-80, 2013.
[Journal]
6)  Kulkarni V, Valentin A, Rosati M, Alicea C, Singh AK, Jalah R, Broderick KE, Sardesai NY, Le Gall S, Mothe B, Brander C, Rolland M, Mullins JI, Pavlakis GN, Felber BK.
Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.
PLoS ONE. 9: e86254, 2014.
[Journal]
7)  Jalah R, Kulkarni V, Patel V, Rosati M, Alicea C, Bear J, Yu L, Guan Y, Shen X, Tomaras GD, LaBranche C, Montefiori DC, Prattipati R, Pinter A, Bess J, Lifson JD, Reed SG, Sardesai NY, Venzon DJ, Valentin A, Pavlakis GN, Felber BK.
DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques.
PLoS ONE. 9: e91550, 2014.
[Journal]
8)  Kulkarni V, Rosati M, Jalah R, Ganneru B, Alicea C, Yu L, Guan Y, Labranche C, Montefiori DC, King AD, Valentin A, Pavlakis GN, Felber BK.
DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.
J. Med. Primatol. [Epub ahead of print], 2014.
[Journal]
9)  Vargas-Inchaustegui DA, Tuero I, Mohanram V, Musich T, Pegu P, Valentin A, Sui Y, Rosati M, Bear J, Venzon DJ, Kulkarni V, Alicea C, Pilkington GR, Liyanage NP, Demberg T, Gordon SN, Wang Y, Hogg AE, Frey B, Patterson LJ, DiPasquale J, Montefiori DC, Sardesai NY, Reed SG, Berzofsky JA, Franchini G, Felber BK, Pavlakis GN, Robert-Guroff M.
Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.
Clin. Immunol. [Epub ahead of print], 2014.
[Journal]
10)  Vaccari M, Halwani R, Patterson LJ, Boasso A, Beal J, Tryniszewska E, Hryniewicz A, Venzon D, Haddad EK, El-Far M, Rosati M, Pavlakis GN, Felber BK, Al-Muhsen S, Robert-Guroff M, Sekaly RP, Franchini G.
Antibodies to gp120 and PD-1 expression on virus-specific CD8+ T cells in protection from simian AIDS.
J. Virol. 87: 3526-37, 2013.
[Journal]
Click Here to View Expanded Bibliography.

This page was last updated on 6/20/2014.