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CCR Nanobiology Program

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Research

The Nanobiology Program pursues an integrated, multidisciplinary program of basic and applied studies aimed at the design of nanodevices to combat cancer, AIDS and other viral diseases. Steps to achieve the goal involve:

  • To understand the structure and function of biomolecules and their assemblies at the nanoscale
  • To understand engineering principles of Nano machineries used in living cells
  • Use this knowledge to build multifunctional devices for preventing and curing disease

The activities of the Principle Investigators in the Program fall into several broad areas that include membrane structure and function; protein interactions; structural bioinformatics; structural glycobiology; molecular information theory and computational RNA Structure. The investigators are working together to gain an understanding how macromolecules form functional assemblies and networks, and how they enter cells and tissues. In addition the Program encompasses CCR PI adjunct investigators who collaborate with CCRNP and bring their expertise to bear in order to enhance the Nanobiology Program's efforts in the areas of chemistry, high resolution imaging, radiation biology and oncogenomics. The program also forms partnerships with the NCI's broader Nanotechnology Program, other CCR basic research laboratories and clinical branches, as well as with the broader extramural community, to enhance the interface of physics and computational sciences with biology.


Adjunct Investigators

Joseph J. Barchi Jr., Ph.D., Laboratory of Medicinal Chemistry

Jacek Capala, Ph.D., Radiation Oncology Branch

Javed Khan, M.D., Pediatric Oncology Branch

Sriram Subramaniam, Ph.D., Laboratory of Cell Biology

This page was last updated on 11/3/2009.